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Summary Expression Gene Literature (19) GO Terms (5) Nucleotides (56) Proteins (22) Interactants (52) Wiki
XB-GENEPAGE- 985593

Gene Symbol: prph2

Gene Name: peripherin 2 (retinal degeneration, slow)

Synonyms: rds , peripherin 2 , avmd , aofmd , cacd2 , tspan22 , rds38
Add Xenopus synonyms , Nomenclature history


Gene Function: Tetraspanin family integral membrane protein

Protein Function :
May function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. It is essential for disk morphogenesis.


Interactants: Loading ...

Disease Ontology:
   VITELLIFORM MACULAR DYSTROPHY [+]

OMIM Diseases:
   FUNDUS ALBIPUNCTATUS [+]
 

Xenbase Gene ID XB-GENE-985594 XB-GENE-985595 XB-GENE-17339014
Gene Symbol prph2 prph2.L prph2.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq Refseq
Protein NCBI Protein TrEMBL Refseq TrEMBL Refseq Swiss-Prot Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.75760 Xl.81116 Xl.192 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 4 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine prph2 prph2.L prph2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PRPH2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Prph2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN
chicken
GEISHA PRPH2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Three homologs of rds/peripherin in Xenopus laevis photoreceptors that exhibit covalent and non-covalent interactions. [J Cell Sci 1996]
Most recent: Retrograde intraciliary trafficking of opsin during the maintenance of cone-shaped photoreceptor outer segments of Xenopus laevis. [J Comp Neurol 2014]
View All Papers 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 3 terms 2 terms 3 terms
PANTHER prph2
KEGG Pathways K17343 K17343 K17343
KOG [R] Tetraspanin family integral membrane protein
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Prph2 Ab2 , Prph2 Ab1 Prph2 Ab2 , Prph2 Ab1
ORF prph2.L ORF1 prph2.S ORF1
Affymetrix 1.0 StrEns.3074.1.S1_at Xl.192.1.S1_at
Affymetrix 2.0 Xl2.17944.1.S1_at [+] Xl2.192.1.S2_at [+]

Symbol legend[+]
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