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Summary Expression Gene Literature (108) GO Terms (19) Nucleotides (153) Proteins (37) Interactants (286) Wiki
XB-GENEPAGE-985622
Gene Symbol:
dtl

Gene Name:
denticleless E3 ubiquitin protein ligase homolog

Synonyms:
cdt2 , ramp , dcaf2 , l2dtl ( Add synonyms , Nomenclature history )

Gene Function:
WD40 repeat-containing protein L2DTL

Protein Function :
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also ...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-985623 XB-GENE-985629 XB-GENE-6254292
Gene Symbol dtl dtl.L dtl.S
Chromosome Chr05 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 395039
444035
735103
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine dtl dtl.L dtl.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DTL OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dtl MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dtl Ensembl
zebrafish
ZFIN, AGR dtl ZFIN Ensembl
chicken
GEISHA DTL Ensembl
fruit fly
worm
Publications
First Gonadotropin-releasing hormone receptor expression in Xenopus oocytes., Mol Endocrinol 1990  
Most Recent Association of A Novel Splice Site Mutation in P/Q-Type Calcium Channels with Childhood Epilepsy and Late-Onset Slowly Progressive Non-Episodic Cerebellar Ataxia., Int J Mol Sci 2020              
All View All Papers 1 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 16 terms 16 terms
PANTHER dtl
KEGG Pathways K11790 K11790 K11790
KOG [S] WD40 repeat-containing protein L2DTL
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks dtl
Mutants Xtr.dtlemHorb
ORFs dtl ORF1 dtl.L ORF1 dtl.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

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