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Summary Expression Gene Literature (122) GO Terms (19) Nucleotides (155) Proteins (38) Interactants (304) Wiki
Gene Symbol:

Gene Name:
denticleless E3 ubiquitin protein ligase homolog

cdt2 , ramp , dcaf2 , l2dtl ( Add synonyms , Nomenclature history )

Gene Function:
WD40 repeat-containing protein L2DTL

Protein Function :
Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also ...[+]

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External Links:
Xenbase Gene ID XB-GENE-985623 XB-GENE-985629 XB-GENE-6254292
Gene Symbol dtl dtl.L dtl.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 395039
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dtl dtl.L dtl.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards DTL OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Dtl MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Dtl Ensembl
ZFIN, AGR dtl ZFIN Ensembl
fruit fly
First Gonadotropin-releasing hormone receptor expression in Xenopus oocytes., Mol Endocrinol 1990  
Most Recent Effect of 158 herbal remedies on human TRPV1 and the two-pore domain potassium channels KCNK2, 3 and 9., J Tradit Complement Med 2020              
All View All Papers 1 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 9 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 19 terms 16 terms 16 terms
KEGG Pathways K11790 K11790 K11790
KOG [S] WD40 repeat-containing protein L2DTL
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dtl
Mutants Xtr.dtlemHorb
ORFs dtl ORF1 dtl.L ORF1 dtl.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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