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Summary Expression Gene Literature (25) GO Terms (20) Nucleotides (44) Proteins (26) Interactants (163) Wiki
XB-GENEPAGE-985798
Gene Symbol:
f2r

Gene Name:
coagulation factor 2 (thrombin) receptor

Synonyms:
coagulation factor II receptor , PAR1 , Protease-activated receptor ( Add synonyms , Nomenclature history )

Gene Function:
G protein-coupled receptor

Protein Function :
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-985799 XB-GENE-985800 XB-GENE-17342042
Gene Symbol f2r f2r.L f2r.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100493325
378526
108707268
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine f2r f2r.L f2r.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards F2R OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR F2r MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR F2r Ensembl
zebrafish
ZFIN, AGR f2r ZFIN Ensembl
chicken
GEISHA F2R Ensembl
fruit fly
worm
Publications
First Ligand cross-reactivity within the protease-activated receptor family., J Biol Chem 1996  
Most Recent Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain., J Biol Chem 2015  
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 4 terms 3 terms
PANTHER f2r
KEGG Pathways K06752 K03914 K03914
KOG [T] G protein-coupled receptor
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks f2r
Clones Horizon Horizon Source BioScience Horizon

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