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Summary Expression Gene Literature (8) GO Terms (4) Nucleotides (51) Proteins (18) Interactants (201) Wiki
XB-GENEPAGE-986625

Gene Symbol: rasgrp2

Gene Name: RAS guanyl releasing protein 2 (calcium and DAG-regulated)

Synonyms: xrasgrp2 , rasgrp2-a , rasgrp2-b ( Add Xenopus synonyms , Nomenclature history )

Gene Function: Ras1 guanine nucleotide exchange factor

Protein Function :
Functions as a calcium- and DAG-regulated nucleotide exchange factor specifically activating Rap through the exchange of bound GDP for GTP. May function in cell aggregation and adhesion.

Interactants: Loading ...
Disease Ontology: platelet-type bleeding disorder 18

OMIM Diseases: BLEEDING DISORDER, PLATELET-TYPE, 18; BDPLT18

 
Xenbase Gene ID XB-GENE-986626 XB-GENE-986629 XB-GENE-6256357
Gene Symbol rasgrp2 rasgrp2.L rasgrp2.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide RefSeq RefSeq
Protein NCBI Protein RefSeq Swiss-Prot RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine rasgrp2 rasgrp2.L rasgrp2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards RASGRP2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Rasgrp2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR rasgrp2 ZFIN Ensembl
chicken
fruit fly
worm
WORMBASE
Publications
First XRASGRP2 expression during early development of Xenopus embryos., Biochem Biophys Res Commun 2008          
Most Recent RASGRP2 Suppresses Apoptosis via Inhibition of ROS Production in Vascular Endothelial Cells., ScientificWorldJournal 2019                
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 4 terms
PANTHER rasgrp2
KEGG Pathways K12361 K12361
KOG [T] Ras1 guanine nucleotide exchange factor
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino rasgrp2 MO1 , rasgrp2 MO2 , rasgrp2 MO3 rasgrp2 MO1 , rasgrp2 MO2 , rasgrp2 MO3 rasgrp2 MO1 , rasgrp2 MO2 , rasgrp2 MO3
ORF rasgrp2.L ORF1 rasgrp2.S ORF1 , rasgrp2.S ORF2
Affymetrix 1.0 StrEns.3613.1.S1_at Xl.9480.1.S1_at
Affymetrix 2.0 Xl2.14799.1.S1_at Xl2.9480.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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