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Summary Expression Gene Literature (6) GO Terms (6) Nucleotides (194) Proteins (36) Interactants (141) Wiki
XB-GENEPAGE-989848
Gene Symbol:
eif2ak3

Gene Name:
eukaryotic translation initiation factor 2 alpha kinase 3

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
eIF-2alpha kinase PEK/EIF2AK3

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Wolcott-Rallison syndrome

OMIM:
EPIPHYSEAL DYSPLASIA, MULTIPLE, WITH EARLY-ONSET DIABETES MELLITUS

External Links:
 
Xenbase Gene ID XB-GENE-989849 XB-GENE-17340900 XB-GENE-989852
Gene Symbol eif2ak3 eif2ak3.L eif2ak3.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100190763
403386
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine eif2ak3 eif2ak3.L eif2ak3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards EIF2AK3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Eif2ak3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Eif2ak3 Ensembl
zebrafish
ZFIN, AGR eif2ak3 ZFIN Ensembl
chicken
GEISHA EIF2AK3 Ensembl
fruit fly
worm
Publications
First A heterozygous activating mutation in the sulphonylurea receptor SUR1 (ABCC8) causes neonatal diabetes., Hum Mol Genet 2006  
Most Recent Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring., Mol Cell 2019                  
All View All Papers 2 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 0 term 2 terms
PANTHER eif2ak3
KEGG Pathways
KOG [J] eIF-2alpha kinase PEK/EIF2AK3
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks eif2ak3
Morpholinos eif2ak3 MO1 eif2ak3 MO1 eif2ak3 MO1
Clones Horizon Horizon Source BioScience

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