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Summary Expression Gene Literature (5) GO Terms (7) Nucleotides (200) Proteins (47) Interactants (110) Wiki
XB-GENEPAGE-991641
Gene Symbol:
best2

Gene Name:
bestrophin 2

Synonyms:
vmd2l1 , best2-a , best2-b ( Add synonyms , Nomenclature history )

Gene Function:
Bestrophin (Best vitelliform macular dystrophy-associated protein)

Protein Function :
Forms chloride channels.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-991642 XB-GENE-991648 XB-GENE-6255790
Gene Symbol best2 best2.L best2.S
Chromosome scaffold_185 chr3L Scaffold20
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 394571
380009
398601
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine best2 best2.L best2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BEST2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Best2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Best2 Ensembl
zebrafish
ZFIN, AGR best2 ZFIN Ensembl
chicken
GEISHA BEST2 Ensembl
fruit fly
FLYBASE Best2 Ensembl
worm
Publications
First Two bestrophins cloned from Xenopus laevis oocytes express Ca(2+)-activated Cl(-) currents., J Biol Chem 2003                    
Most Recent ATP activates bestrophin ion channels through direct interaction., Nat Commun 2018  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 4 terms 4 terms
PANTHER best2
KEGG Pathways K13879 K13879 K13879
KOG [R] Bestrophin (Best vitelliform macular dystrophy-associated protein)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks best2
Morpholinos best2 MO1 , best2 MO2 best2 MO1 , best2 MO2 best2 MO1 , best2 MO2
ORFs best2.L ORF1 best2.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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Version: 4.14.0
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