Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (3) GO Terms (15) Nucleotides (144) Proteins (34) Interactants (73) Wiki
XB-GENEPAGE-992426
Gene Symbol:
bcl2l2

Gene Name:
BCL2-like 2

Synonyms:
bclw , bcl-w , xr1 , bcl2l2-a , bcl2l2-b ( Add synonyms , Nomenclature history )

Gene Function:
Anti-apoptotic Bcl-2 family proteins, prevent opening of mitochondrial porin channel

Protein Function :
Could be the homolog of mammalian Bcl-W.



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-992427 XB-GENE-992432 XB-GENE-6252167
Gene Symbol bcl2l2 bcl2l2.L bcl2l2.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 496475
444156
397930
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine bcl2l2 bcl2l2.L bcl2l2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BCL2L2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Bcl2l2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Bcl2l2 Ensembl
zebrafish
chicken
fruit fly
worm
Publications
First Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak., J Cell Biol 2007                
Most Recent Mcl1 protein levels and Caspase-7 executioner protease control axial organizer cells survival., Dev Dyn 2020                
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 2 terms 3 terms
PANTHER bcl2l2
KEGG Pathways K02163 K02163 K02163
KOG [T] Anti-apoptotic Bcl-2 family proteins, prevent opening of mitochondrial porin channel
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks bcl2l2
ORFs bcl2l2 ORF1 bcl2l2.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556