Gene Symbol: insm1 Gene Name: insulinoma-associated 1 Synonyms: IA1 Add Xenopus synonyms Gene Function: zinc finger transcription factor Interactants: ins(6) , gcg(5) , hhex(5) , pax6(4) , ptf1a(4) , celf3(3) , neurod1(3) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001083358|Xenopus (Silurana) tropicalis insulinoma-associated 1 (insm1), mRNA AAGCCGTGCAGCTGCAGCACCTCGGACAGTGCAGGAGAGCGGGAGGCACAGCAGCACCTCGGACAGTGCCAGACAGCCGCTTATTAACTATTAACTCCCCACACTCCCTGAGACACTCCTTCGCACCAACATGCCTAAAGGGTTTCTGGTGAAACGCAGCAGGAAGTCCCCGCCGGTGTCCTACCGGGTGCGGGAAGAAGAAGAGCCCCGCGGGGAGTCGCTCCCGGGATGGATGCTCTTAGCTACAATGTGCCCGACCGGTGGGGCCCCGCCGCCCTGCAGCCCAGACAGAGCCACCCAGGCCCCATGCTGCAGCAGCCCCCGGCCGCCCCCCGCCGGTCAGTTCGGGAACCCGGACACAGTGCAGCAGGCTCTGTACAGCCCGACCCGCCCGGTGAGCAGGGAGCAGCGGGAAAGGAAATACCTGGGATCCCCGGTGTCTGCGGAGTCCTTTCCGGGCCTGGGCACCTCCAGCGAAGCGCTACTCTACCCTCCCACAGGCACTGCCAATGGGCATCACGGACTGGCACTGCTGCCCCCGGTCTCTTCCTCCTCTTCAGTCAGCCGAAGCCAAGGCAAGAGGCCGGCCCCGGAGCCCGACAGCAAGCCCGCCGCTATGCCCGGCACTGGCCCAGGGGCCACAAGCAGCTCGGCCCCCAGCAAGCCCCCTGCGGCCAAGAAAACCAAAGCCATCCGCAAACTGACCTTTGAAGACGAGGTGACCACATCCCCGGTGCTGGGTCTGAAAATCAAGGAAGGACCGGTGGAGCCCCCCCGCCCCAGGGCAGCCAGCTCCGGGCCCCGACCCCTGGGGGAGTTCATCTGCCAACTGTGCAAGGAGGAGTACAGCGACCCCTTCTCCCTGGCGCAGCACAAATGCTCCAGAATCGTGAGGGTCGAGTACCGCTGCCCAGAGTGCCACAAGGTGTTCAGCTGCCCGGCCAACTTGGCATCGCACCGCCGCTGGCACAAGCCCCGACCCCCAGTCGCCTCCACAGCCCAAGCCAAGGAGGAGCCACTGAGTGACCGGGACACCCCCAGCCCAGGGGTCTCCGAGTCCGGCTCAGAAGATGGGCTGTACGAGTGCCCCCGGTGTGCCCGCAAGTTCCGCCGCCAGGCTTATCTGAGGAAGCACCTGCTGTCGCACCAAGCAGCCAAGGAGCCGGAGGAGCCCGGTGTCATGATGTTCCCGGGGGAGGAGCAGCGAGCCAAGAGCCCCCCCAGCCTGAATGCCCAGGAGTGCCACCCGTGCCCGGTGTGTGGGGAAACATTCCCGGGGAAGAGCAGCCAGGAGCGCCACATCCGCCTCCTCCACTCCTCCCAGCTGTACCCCTGCAAGTACTGCCCCGCCACCTTCTACAGCTCCCCCGGCCTGACCCGCCACATCAACAAGTGCCACCCCTCCGAGAACCGGCAGGTCATCCTGCTCCAAGTGCCGGTGCGCCCGGCCTGCTGACTTTGTGGGGACTTGTTCCAAGGAGAAATGTAGGGGTGTGCCCACCCCTCCCCCACATGGACCTGACGGGGGCCCCAAAATGAGAATATTGCACCAATTGTAAGTGCCGGGGGGCTGCAGCATATTGCGGGGCAGTGTGTTGTCTCTCTCAGGCACTTATGGAATCAGATACTTTGGGCCAATGGGCACAGAGGTCACAAGGTGCCCCTAAAGGGCCAATAAAACGGACCATCTTGCACTAATGGGGCGAGGGAAGTGCCGCTAGCCATGCCTGCTGCCCCCCCCGGTGCCCACCCAACCCCCACACAGGTTTCCAACAAGCCCCCGCTGTGGCTACGGGACTCGCATGCCTGACTAGTACTGTGCCTTCCCGGTGCATCCAATGCCCACAGGGCACTGCCACCTGCCAAATCAGCGACCACAGCAGCCATAGGCCCAAGTGCATTACATTGTGGTTATTGTGCTTTAAAGCGACCCAGAGTTATCCGAGTAACCCCTCAGTGCCCAGGGAGCCCGCTATGCCCAAGTCATGCCCATGGGCACTGAGGGGAGACGGAATGGGAAGGGAGAGCACTTTCTGCTTTATTTATTGTGTTGATAATATTCTCTGTGTCCGTGCTAAATGCCTGTGCAAGGATTCTACAGTAAGTTATGTATGTTGTCCCATTGGCCTCATAGAGACAGCGCTGAGCCATAGCGGGGCTAGTGCTGCTGCCTGTGAGAGCTCAGATGGGGCAACGCTTTAGGGTGGGGGAGGGGTGGGCAAGCCATATGCTCACTGTACTTTTTAAAAATGTCAGATCGCAGGGTTTGTCATGTAATTGATGTGCTTAACCCCTAAAATGCTGGAGGGAGCTGCGGTAATTCGCAGAGAAGCCCCTGCCCAATCTGGCTGCGTTTAACCCGTCACTGCCATTTGGGAGAGCCCTTCTAGCAGCAGTTTATGTCGCCTGTGCTTTTGTAGCCTTTCCTCTTGTCTTGATATAAATGTGCTTTCTAGCCTAAGGGGTTAATGTTCTGCCTTGATGCCCCCCGGCCTGCACACAACTATACCATTAGCTTTATACACTGGCCGGGGGGCTGCTCAGCTCTGTCTTTCTCTCTTCTCAGCCCCAGCTGTGGATTTTGGGGGGGGAGGAGGAGACTTTACTTTAGTCTTAGCCACAAATGCCTTGAAGTCATTATTGTCTCTTTAATAACTCTGGAGTAAGCTGTAGCGACTGCCTGGTCCCCCCCAGTGTAGGGACCCACAATCCATCCCAATACAGGGATCCTGGCTACATTAAATCAACTTTTTGTCACGTGTTTTGTCCCCCCCCCCTCTAAAATATCTTTCTGTATGCCCCCCCCCATGCGTTTACTATCCAAAATGTATATGTTGATTTTATGATTAATTATGTTTATTTATTTTTATTTATTTATGAGAATGATGAAGATATGACTTTTATTCGATCTCTTTCATTGCCTAGATATATAAATATATATATTTTGCCATGACTTCTCACTGTGGATTTCAGCCTTTTCTTTGCTTTAATACAACTGAATGATGAGAGAATGTAGATCTGGGCACATTCCGGACCTTGAGGGCAGCCAGCGCTCCGACCTTATTATAGCTCTTATGTCTAGAGAAATCTCTTTTGTACACAACATTATTTTCCTAACTGTAATAGGCATTTATAGAGTGCTTCAATAGAACTGTTCTACTGTGTAACGATTTGCTATTCAAATAAAATTATTTTCCAATTCAAATCAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001110719|Xenopus laevis insulinoma-associated 1 (insm1), mRNA CCCACGCGTCCGCTTGCACAGAGAAAAAGCGTTACAGCCTGCAGCACCTCGGACAGTGCAGGAGAGCGCGAGCAGCAGCAGCAGCAGCAGCACCTCGGACAGTGCCAGACACAGCGAGCGCCAAAGCATTCAGCCCAGACTCACTGGGACCGACCCAACATGCCTAAAGGTTTCCTGGTCAAGCGCAACAGGAAGTCCCCGCCGGTGTCCTACCGAGTGCGGGAAGATGAGGAGAACCGCGGGGAGTCGCTCCCGGGCTGGATGCTCTTAGCGACCATGTGTCCCACCGGCGGGGCCCCACCTCCTTCCAGTCCCGAAAGACTCGCCTCCGCGGCCCCATCCTGCAACAACCCCCGGCCGCCCCCCGCCGGTCAGTTCGGGAACCCCGAGGCGGTGCCGCAGACTCTGTACAGCCCGACCCGCCCGGTCAGCCGGGAGCAGCGCGAGAGGAAATACCTGGGATCCCCGGTGTCTGCAGAGTCTTTCCCGGGCCTGGGCAGCTCCAGCGAGGCGCTCCTCTTCCCTCCCACGAGCACTGCCAATGGGCATCACGGACTGGCGCTCCTGCCCCCGGTCTCCTCCTCCTCTTCCATCAGCCGCACTCACGGCAAGAGACCGGCCCCCGAGCCAGACGTTAAAGCCGGCGCTGCCCCCGGCACTGCCTGTAAACCCCCCGCCGCCAAGAAAACCAAAGCCATCCGCAAGTTGACCTTTGAGGACGAGGTGACAACATCCCCGGTGCTCGGGCTGAAAATCAAGGAAGGACCGGTGGAGCCTCCCCGCCCTCGTGCCCCCAGCTCCGGCCCCCGACCCCTGGGCGAGTTCATCTGCCAGTTGTGTAAGGAGGAGTACAGCGACCCCTTCTCTCTGGCACAACACAAATGCTCCAGAATCGTCCGGGTAGAATACCGCTGCCCAGAGTGCCACAAGGTGTTCAGCTGCCCCGCCAACCTGGCCTCCCACCGCCGCTGGCACAAGCCCCGACCCCCAGCCGTCCCCGCAGTCCAACCCAAGGAAGAGGCCCTGAGTGACCGGGACACCCCCAGCCCCGAGTCCGGCTCAGAAGACGGTCTGTACGAGTGCCCGCGGTGCGCCCGCAAGTTCCGGCGTCAGGCTTATCTGAGGAAACACCTGCTGTCGCACCAAGTGACCAAGGAGCCGGAAGAGGCCGGTCACATGATGTACCAGAGCGACGAGCAGCGGCCTCAAGCCAAGAGTCCCCCCAGCCTAAATGTCCCCCAGGAGTGTCACCCGTGCCCTGTGTGCGGAGAAACCTTCCCGGGGAAGAGCAGCCAAGAGCGTCACATCCGCCTCCTTCATTCCTCTCAGCTGTACCCCTGCAAATACTGCCCCGCCACCTTCTACAGCTCCCCCGGCCTCACCCGCCACATCAACAAGTGTCACCCCTCCGAGAACAGACAGGTCATCCTGCTGCAAGTGCCCGTGCGCCCGGCCTGCTGAGCCCGCAACAACTTCTTAGGACTTTTTGGGGAGTTGCGCAAAGGATGATTGACGTGTCAGCTCCTCCCCCCAAACACGGACCTATTGGGGTCCCCAGAAGTATAAAGTTGAACCAATTGAAAGTGCCGGGGACATGCGACATATTGCGGGCCAGTGTGGGAGTCTCAGGCGGCACTTATGAAATCAGATACATTAGGGGTCATTCGTTGGGTCAGACTGCAGATCTAGGGGAGCGGGTAGAGACCTTCAGTCCTGTTGCAGAGCGACCTGGTGCTGAACTCTGCCTGCTGTGCCCCTTAAATGGACAATGGAAGGGACCATCTTGCACTAAAGGGGGGGGGGGTTGTGCCCTACCGATACCTATAGACTCACTGCCCCAACACTCACACACACACACTCCCCTTAAAGATTTTCAAGAAGCTCCTGCTGTGGCCACGGGACTCGCATTCCTGACTAGTCTGTGCCTTTCCCGACGCATCCAATGCCATTCTGCCCACAGGGCACTGCCACCCGCCAAATCAGCAGCCGACCACAGCAGCCATAGGCCCAAGTGCATTACATTGTGGTTATTGTGCTTTAAAGCGACTCAGCGTTATCTCCATGACCCCCCTCAGTGCCCAAGTGGTCCATTCCGACCCGGGGACACTCACAACGGGGGAGGGGGAGCACTTTCTGCTTTATTTATTGTGTCGATTTCCTCGGAATCTGTGTCTGTGCAAATGACTGTGTCCGCCCATGAGTCGCTTCTACAATGAGATAAATGTATATTGCCCAGTTGCCATCCACTCACTGTTACAGCATTTGTGATGCCCTGACACTCGCCTCCCCCCCCCGCCAGTTGGATGTGCTCATTCCAGTGACTGCTGCTTGTGACACCGACAGCTCAGAATTGGGAGGGCAAAGTTATTTTTTTTCGGGGGGGGCTCATTTGTTCACTGTATGTTTTAAAAATGGTCAGATCGCAGGGTTTGTGGTGTAAGTGATGTGCTTAACCCCTGCAATGCTGGAGGGAGCTGCAGTAATTTGTAGAGTATCCCCCCCTCCAGTCTGACTCAGTTAAACCCATCGCTGCCATTAGGGAGACACCCCCCCCCCTCCCAGCAGCAGTTAATGTCGCCTGTGCTTTTGTAGCCTCTTGTCTTGATATCAATGTGCTTTGTAGCCTATGGGGTTAATGTTCTGCCTTGATGCCCCCCGGCCTGCACTCTCTCTACTCTCCCATTAGCTTTATACACTGGCCGGGGGGCTGCTCAACTCTGTCTTTCTCTCCTCATTTTTGGGGGAAGGAGGAGACTTTACTTTAGTCTTAGCCACAAATGCCTTGAAGTCATTATTTTCTCTATTAACTCTGGAGTAGTCACTGCCTTGTCCCCCCCAGTGTAGGACCAACACTCCATGGACCTTGGCTCCTTTAAACTTTTGTGTCACTTGTTTTCTTCCCCCTCATTCTCTAAAATCTGTTGTGTAAGCCCCGCCCCCATGCGTTCACTATCCCAAATGTATATGTTGATTTTATGATTAATTATGTTTATTTATTTTTTATTTATTGACGAGAATGATGAAGATATGACTTTTATTCGATCTCTTTCGTTGCCTAGATATACATATATATATTTTGCCATGACTTCTCACTGTGGATTTCAGCTTTTCCTTCGCTTTAAACCCTGAACTGAACGAGAGAATGTAGATCATTGTCACCTTCTTATAGCTCTTATGTCTAGACAAAATCTCTTTTGTACACAACATTATTTTCCTAACTGTAATAGGCATTTATTAGAGTGCTTCAATAGAACTGTTCTACTGTCTTAACGATTTGCTATTCAAATAAAATTATTTTCAAATTCAAAAAAAAAAAAAAA
Protein		Refseq >NP_001076827|insulinoma-associated 1 [Xenopus (Silurana) tropicalis] MPKGFLVKRSRKSPPVSYRVREEEEPRGESLPGWMLLATMCPTGGAPPPCSPDRATQAPCCSSPRPPPAGQFGNPDTVQQALYSPTRPVSREQRERKYLGSPVSAESFPGLGTSSEALLYPPTGTANGHHGLALLPPVSSSSSVSRSQGKRPAPEPDSKPAAMPGTGPGATSSSAPSKPPAAKKTKAIRKLTFEDEVTTSPVLGLKIKEGPVEPPRPRAASSGPRPLGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECHKVFSCPANLASHRRWHKPRPPVASTAQAKEEPLSDRDTPSPGVSESGSEDGLYECPRCARKFRRQAYLRKHLLSHQAAKEPEEPGVMMFPGEEQRAKSPPSLNAQECHPCPVCGETFPGKSSQERHIRLLHSSQLYPCKYCPATFYSSPGLTRHINKCHPSENRQVILLQVPVRPAC	Refseq >NP_001104189|insulinoma-associated 1 [Xenopus laevis] MPKGFLVKRNRKSPPVSYRVREDEENRGESLPGWMLLATMCPTGGAPPPSSPERLASAAPSCNNPRPPPAGQFGNPEAVPQTLYSPTRPVSREQRERKYLGSPVSAESFPGLGSSSEALLFPPTSTANGHHGLALLPPVSSSSSISRTHGKRPAPEPDVKAGAAPGTACKPPAAKKTKAIRKLTFEDEVTTSPVLGLKIKEGPVEPPRPRAPSSGPRPLGEFICQLCKEEYSDPFSLAQHKCSRIVRVEYRCPECHKVFSCPANLASHRRWHKPRPPAVPAVQPKEEALSDRDTPSPESGSEDGLYECPRCARKFRRQAYLRKHLLSHQVTKEPEEAGHMMYQSDEQRPQAKSPPSLNVPQECHPCPVCGETFPGKSSQERHIRLLHSSQLYPCKYCPATFYSSPGLTRHINKCHPSENRQVILLQVPVRPAC

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.53127	Xl.14733
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		7 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	INSM1
mouse		MGI	Insm1	All(4) Targeted, other(1) Targeted, knock Out(3)
zebrafish		ZFIN ZFIN	insm1b insm1a	1 Lines(s)

Publications
First:		Developmental expression of FoxJ1.2, FoxJ2, and FoxQ1 in Xenopus tropicalis. [Gene Expr Patterns 2006]
Most recent:		Transient expression of Ngn3 in Xenopus endoderm promotes early and ectopic development of pancreatic beta and delta cells. [Genesis 2012]
		View All Papers 2 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		nucleic acid binding zinc ion binding
Biological:
Cellular Component:		nucleus
EC:
KOG:		[K] Transcription factor (contains Zn finger)

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.9375.1.A1_s_at	Xl.14733.1.A1_at
Affymetrix 2.0			Xl2.14733.2.S1_at [+] Xl2.14733.1.A1_at

Symbol legend[+]

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   - Literature Or Expression Images