Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (21) GO Terms (19) Nucleotides (29) Proteins (22) Interactants (116) Wiki
XB-GENEPAGE-993851
Gene Symbol: slc6a5

Gene Name: solute carrier family 6 member 5

Synonyms: glyt2 , xGlyT2 ( Add synonyms , Nomenclature history )

Gene Function: transmembrane solute exchange

Protein Function :
Sodium- and chloride-dependent glycine transporter. Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: hyperekplexia 1

OMIM: HYPEREKPLEXIA 1; HKPX1 [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
 
Xenbase Gene ID XB-GENE-993852 XB-GENE-17337534 XB-GENE-1029878
Gene Symbol slc6a5 slc6a5.L slc6a5.S
Chromosome scaffold_84 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100495275
108713447
100301957
mRNA NCBI Nucleotide NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL NCBI Protein TrEMBL RefSeq TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine slc6a5 slc6a5.L slc6a5.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SLC6A5 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Slc6a5 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR slc6a5 ZFIN Ensembl
chicken
GEISHA SLC6A5 Ensembl
fruit fly
worm
WORMBASE
Publications
First Cloning and expression of a spinal cord- and brain-specific glycine transporter with novel structural features., J Biol Chem 1993  
Most Recent Distribution and neuronal circuit of spexin 1/2 neurons in the zebrafish CNS., Sci Rep 2019                
All View All Papers 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 18 terms 0 term 4 terms
PANTHER slc6a5
KEGG Pathways K05038
KOG [T] Sodium-neurotransmitter symporter (alt_id KOG:3660)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks slc6a5
Clones Horizon Horizon Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.13.0


Major funding for Xenbase is provided by grant P41 HD064556