[provisional- machine annotated only] Gene Symbol: c1r [Predicted: Source is Human Entrez Gene] Gene Name: complement component 1, r subcomponent [Predicted: Source is Human Entrez Gene] Add Xenopus synonyms Gene Function: Trypsin Interactants: c1s(6) , masp1(2) , masp2(2) , uvs.2(2) , abcc1(1) , bmp1(1) , bmp2(1) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >BC096515|Xenopus tropicalis complement component 1, r subcomponent-like, mRNA (cDNA clone IMAGE:7005348), partial cds CTGGCAGCAGAGGCAGAGACCCTACAGTACCATGTGGCGCTATGTGGTCCTGCTCCTGGGAACTGTATCCTGCTCCCAAACCAGCAATAACAGCCCACTGTCTGGAACCATCACGTCCCCCAATTACCCCAAACTGTACCCCAGATTCAATGACAGCACCTGGGATATTATTGTCCCTGAAGGGTATTACGTTTCCCTCAACTTCTCCGTGTTTGATATTGAACCCTCCGAAAACTGCTCCCACGGCTTTGTGAAGGTAATGGCCGATGGGAAGGAGCTGGGCCAATTCTGTGGTCCCGTGAACTCCTCCAGCCACCCTGGCAACCGCCAGTTTGTGTCACTAGGAAACCAAATGAGAATTCACTTCCAGTCTAATTTCTCCAAGGAGATGGATGGGGACATCATCCAATACAAAGGGTTCCAGGCCTTTTATCAGGCCATTGTTGTGACCTGTGAAGACCCCCCGGTTCTGACCAATGGACAGTATACATTCCTGACGGCACCAGGGAGACTGGAATACAGATCTGCTATTCAGTATCAATGTAACGCCCCTTACTACAACATGGTGACCCCTAACGCCAGCGACACGTACACATGTTCCGCCCAGCGAGAGTGGAGGGATGAGCACGGAGGGAATAGGATCCCACGCTGCAGGCCAGTGTGCGGGAAGCCAGGAGATCCTGTGGGAAGCTTTGGGCGTATCCTTCACGGTAAGAAGGCAGATCCTGGGAACTTCCCTTGGCAGGTTTATGTTTCAAGATATGGAACGGCCGGCGGGGCGCTGATTGGGGAGCAGTGGGTGCTCACAGCAGCCCAAGTACTTCCCGATGATAAAGAGAAGCAAGACCTGGCTGATGTGCACGTCTATATGGGGAGTGTGGAAATGAAACACCTAAAGGAGCTGGGCACCCACCCGGTCGAGGCATTCTACATGCACCCCAACTTCAACAGGAACAACTACGACAATGATATTGCTCTAATACGACTGAAAAATCCCATTGTCATGAACCAAAATGTGTCTCCAATCTGCCTGCCCAGCCCACAGGATGAAGATGATATTTACCAGAAAGATAGAATTGGCTATGTGAGCGGCTATGGGGTGAACGAGAACCGCGACATCCCCAATGAGCTCCGCTACGTCAGCGTGCCAATGGCCAGCAGGCAGGACTGTAAGGCTTATTTAAATAAGAAGAGGCCCATTAGGAACCCCAGCCATGAGGAGAGATATCTATTTTCCAGAAACATGTTCTGTGCCGGATTCCCCGAGGGCTCACTTAATAAAGGAGACTCATGTAGGGGGGACAGTGGTGGGGCCTATACTACCCAAAACAAGCAGGACACCTGGGTGGCCACAGGGCTTGTTTCATGGGGCTTTGGCTGTGGCCAGGGCTATGGGTTCTACACTAAGGTCAGTAATTATGTGGAATGGATAAAGAGCTATGTGGGTGAGGATATATAACGTTCCATAGGAGCGCTATAGCGATAAACATGGTACATCTCTATGTACTTTCATCATGGGGTTTGATTCACTCTTTTAATTACATTAACAGCCCCCTCTAATGTAAAAGCTACTGAAAGTGTTTGGGGTCAGGGAATAATCGCTGGGGGTAAATAGGGTAATACAACAACAGGCACTAATATTAGTCCTGGGCTAAGCAACCCATAGCAACCAGTCAGATATTTTCAGACCAGAAAATGCTGATTTTACCCACTTTGTTTATATCTATAATTATAATTGTGTTAATTTTGCAGCCTGTTATGCATAAAATGTTTAATAATAAAGTCCAAATTCAGTTCAAGGAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001092847|Xenopus laevis complement component 1, r subcomponent (c1r), mRNA CAGAGACCATACAGAATCATGTGGCATTATTTGGTCCTGCTCCTGGGAGCTGTAGTCTGCTCACAAAACAGCAACAACAGCCCACTCTCTGGAACCATCACTTCACCCAATTACCCTAAACTGTACCCGAACTTCAATGAGAGCACCTGGGATATTAACGTCCCTGAAGGTTACCACGTATCGCTCAACTTCTCGGTGTTTGATATTGAACCCTCCGAAAACTGTTCCTGTGGCTTTGTTAAGGTAATGGCTGACGGGAAGGAGCTGGGCCATTTCTGTGGTCCCATGAACTCATCAGCTCATCCCGGCAACCGCCAGTTTGTGTCACAAGGAAACCAAATGACAATTCACTTCCAGTCCAATTTCTCCGAGGAGATGGATGGGGGCATCATTCCATACAAAGGTTTCCAGGCCTTTTATCAGGCCATTGTTGTGATTTGTGAAGATCCTCCGGTTCTGACCAATGGACAATACAAGTTCCTGACGGCACCAGGCAACCTGGAATACAAATCTGTTATTCAATATCAATGTAACAGTCCATACTACTACATGGTGACCCCTAATGGCAGTGACACGTTCTCATGTTCAGCCCAGCGAGACTGGAGAGATGAGCACGGAGGAGATAAGATCCCAAGGTGCAGACCAGTATGCGGGAAGCCAGAAAATCCAGTGACAAGCTTTGGGCGCATCCTTCACGGTAAAAAGGCTGAGCCTGGGAACTTCCCTTGGCAGGTTTATGTCTCAAGATATGGAACGGCCGGAGGGGCACTGATTGGAGAGCAGTGGGTGCTCACAGCAGCCCAAGTACTTCCTGATAATGTTGAGAAGCAAGACCTGAATGATGTGCTTGTCTATATGGGGAGCTTGAACATGAAAAACCTAATGGAAATGGACACCTACCCGGTTGAGGCATTCTATATGCACCCTAACTTCAACAGGAATAACTATGACAATGACATTGCTCTTATCCGGTTGAAAAATCCAGTGGTCATGAACCAAAATGTGTCTCCAATCTGCCTGCCTAGCCCAGAGGATGAAGATGACATTTACCAGAAAGATAGAGTTGGCTACGTGAGTGGATATGGAAAGACAGAGAACCACAAGGTTGCCAATGAACTCCACTACGTCAGCGTGCCAGTGGCCAGCCGGCAGGCCTGTAAGACTTACTTAAACAAGAAAAGGCCGGCAATTAGGTACCCCAGCGATGAGGATAAATATCTGTTTTCCCGAAACATGTTCTGTGCTGGATTCCCTGAGGGCTCTCTTAATAAAGGAGACTCGTGTAGTGGTGACAGTGGTGGGGCCTATACCAGCCAGAATAGGCAGGATACTTGGGTGGCCACAGGGCTTGTTTCATGGGGCTTTAGCTGTGGTCAGGGCTATGGATTCTACACCAAGGTCAGTAATTATGTGGACTGGATTAAAAGCTATGTGGGTGAGGATGCATAGTGTTCCATGAGAGCAATATAGAGATAAACACTGCAAATATCGAACTCTTTCTTTCATAATGGGGTTTGCCTCTTTTAATAAAAAAACAGCCCACTCTAATGTAATGGCTACTGAATGGGGTCATGGAATAATCACTGGGGGTGCAATAGGGTAATACAATAACAGGCACAAACATTGATAGTAACCAGTAGGATATCTTTAGACCAGAAAACTCTGACTTTACCCTCTTTGTTTGTCTCTATAATTGTGTTGTTATTGTAGCCTGTTATGCACAAAAAATGTGTAGAGATAATAAAGTCGAAATTCAGTTCAAGGAAATGATTGAGCTCTCTCCATGTCCAATAAATCTTCAACTAAACTCAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		NCBI Protein >AAH96515|c1rl-prov protein [Xenopus (Silurana) tropicalis] WQQRQRPYSTMWRYVVLLLGTVSCSQTSNNSPLSGTITSPNYPKLYPRFNDSTWDIIVPEGYYVSLNFSVFDIEPSENCSHGFVKVMADGKELGQFCGPVNSSSHPGNRQFVSLGNQMRIHFQSNFSKEMDGDIIQYKGFQAFYQAIVVTCEDPPVLTNGQYTFLTAPGRLEYRSAIQYQCNAPYYNMVTPNASDTYTCSAQREWRDEHGGNRIPRCRPVCGKPGDPVGSFGRILHGKKADPGNFPWQVYVSRYGTAGGALIGEQWVLTAAQVLPDDKEKQDLADVHVYMGSVEMKHLKELGTHPVEAFYMHPNFNRNNYDNDIALIRLKNPIVMNQNVSPICLPSPQDEDDIYQKDRIGYVSGYGVNENRDIPNELRYVSVPMASRQDCKAYLNKKRPIRNPSHEERYLFSRNMFCAGFPEGSLNKGDSCRGDSGGAYTTQNKQDTWVATGLVSWGFGCGQGYGFYTKVSNYVEWIKSYVGEDI	Refseq >NP_001086316|complement component 1, r subcomponent precursor [Xenopus laevis] MWHYLVLLLGAVVCSQNSNNSPLSGTITSPNYPKLYPNFNESTWDINVPEGYHVSLNFSVFDIEPSENCSCGFVKVMADGKELGHFCGPMNSSAHPGNRQFVSQGNQMTIHFQSNFSEEMDGGIIPYKGFQAFYQAIVVICEDPPVLTNGQYKFLTAPGNLEYKSVIQYQCNSPYYYMVTPNGSDTFSCSAQRDWRDEHGGDKIPRCRPVCGKPENPVTSFGRILHGKKAEPGNFPWQVYVSRYGTAGGALIGEQWVLTAAQVLPDNVEKQDLNDVLVYMGSLNMKNLMEMDTYPVEAFYMHPNFNRNNYDNDIALIRLKNPVVMNQNVSPICLPSPEDEDDIYQKDRVGYVSGYGKTENHKVANELHYVSVPVASRQACKTYLNKKRPAIRYPSDEDKYLFSRNMFCAGFPEGSLNKGDSCSGDSGGAYTSQNRQDTWVATGLVSWGFSCGQGYGFYTKVSNYVDWIKSYVGEDA

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.51354	Xl.26367
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	C1R
mouse		MGI	C1ra	All(1) Targeted, knock Out(1)
zebrafish

Publications
First:		Complement components C1r/C1s, bone morphogenic protein 1 and Xenopus laevis developmentally regulated protein UVS.2 share common repeats. [FEBS Lett 1991]
Most recent:		A novel truncated isoform of the mannose-binding lectin-associated serine protease (MASP) from the common carp (Cyprinus carpio). [Immunogenetics 2000]
		View All Papers

Functional Ontologies
GO: Molecular:		chymotrypsin activity complement component C1r activity trypsin activity
Biological:		proteolysis
Cellular Component:
EC:		complement subcomponent C
KOG:		[E] Trypsin

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.39031.1.S1_at
Affymetrix 2.0			Xl2.26367.1.S1_at

Symbol legend[+]

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