Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (49) GO Terms (21) Nucleotides (105) Proteins (30) Interactants (101) Wiki
XB-GENEPAGE-995409
Gene Symbol:
c1s

Gene Name:
complement C1s

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Trypsin

Protein Function :
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sod...[+]


InterPro :
Na trans assoc , Ion trans dom , Volt channel dom sf , Na channel asu [+]

Interactants:
Loading ...

Diseases: 


OMIM:
COMPLEMENT COMPONENT C1s DEFICIENCY; C1SD [+]

External Links:
 
Xenbase Gene ID XB-GENE-995410 XB-GENE-995414 XB-GENE-17330571
Gene Symbol c1s c1s.L c1s.S
Chromosome Chr7 chr7L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 613055
733422
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine c1s c1s.L c1s.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards C1S OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR C1s1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR C1s Ensembl
zebrafish
ZFIN, AGR c1s.1 ZFIN Ensembl
chicken
GEISHA C1S Ensembl
fruit fly
worm
Publications
First Complement components C1r/C1s, bone morphogenic protein 1 and Xenopus laevis developmentally regulated protein UVS.2 share common repeats., FEBS Lett 1991  
Most Recent Complement C1q subunit molecules from Xenopus laevis possess conserved function in C1q-immunoglobulin interaction., Dev Comp Immunol 2020  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 19 terms 5 terms 0 term
PANTHER c1s
KEGG Pathways K01331
KOG [E] Trypsin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks c1s
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list