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Summary Expression Gene Literature (30) GO Terms (8) Nucleotides (356) Proteins (41) Interactants (805) Wiki
XB-GENEPAGE-995709
Gene Symbol:
grn

Gene Name:
granulin

Synonyms:
granulin , gep , gp88 , pepi , pgrn , pcdgf , acrogranin , progranulin , proepithelin , Granulin-1 , Granulin-2 ( Add synonyms , Nomenclature history )

Gene Function:
Epithelin/granulin

Protein Function :
Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3.


InterPro :
Granulin , Granulin fam , Granulin sf , ITPK1 N [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Grn-related frontotemporal lobar degeneration with Tdp43 inclusions [+]

OMIM:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED [+]

External Links:
1/3
 
Xenbase Gene ID XB-GENE-995710 XB-GENE-6253779 XB-GENE-17334567
Gene Symbol grn grn.L grn.S
Chromosome Chr10 chr9_10L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 594884
380370
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine grn grn.L grn.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards GRN OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Grn MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Grn Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR grnb grna ZFIN Ensembl
chicken
GEISHA GRN Ensembl
fruit fly
FLYBASE grn Ensembl
Publications
First An immunohistochemical and morphometric analysis of insulin, insulin-like growth factor I, glucagon, somatostatin, and PP in the development of the gastro-entero-pancreatic system of Xenopus laevis., Gen Comp Endocrinol 1998                  
Most Recent Exploring the relationships between amphibian (Xenopus laevis) myeloid cell subsets., Dev Comp Immunol 2020  
All View All Papers 7 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 8 terms 1 terms 0 term
PANTHER grn
KEGG Pathways K23879 K23879
KOG [T] Epithelin/granulin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks grn
ORFs grn.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info