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Summary Expression Gene Literature (78) GO Terms (20) Nucleotides (1020) Proteins (36) Interactants (1159) Wiki
XB-GENEPAGE-996374
Gene Symbol:
ywhae

Gene Name:
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

Synonyms:
14-3-3 epsilon , 14-3-3epsilon , 14-3-3e ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction

Protein Function :


InterPro :
WH-like DNA-bd sf , Homeobox-like sf , Transposase Tc1-like , Tc1-like DDE dom [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Miller-Dieker lissencephaly syndrome

OMIM:
MILLER-DIEKER LISSENCEPHALY SYNDROME; MDLS

External Links:
1/7
 
Xenbase Gene ID XB-GENE-996375 XB-GENE-17333817 XB-GENE-996381
Gene Symbol ywhae ywhae.L ywhae.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493518
108708028
380397
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ywhae ywhae.L ywhae.S
Phenotype X. tropicalis X. laevis.L X. laevis.S
Smith Morpholino Screen ttpa018g17      
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards YWHAE OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ywhae MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ywhae Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR ywhae1 ywhae2 ZFIN Ensembl
chicken
GEISHA YWHAE Ensembl
fruit fly
worm
Publications
First Synergistic activation by Ras and 14-3-3 protein of a mitogen-activated protein kinase kinase kinase named Ras-dependent extracellular signal-regulated kinase kinase stimulator., J Biol Chem 1994  
Most Recent Conservation and divergence of protein pathways in the vertebrate heart., PLoS Biol 2019                                                      
All View All Papers 3 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 20 terms 0 term 1 terms
PANTHER ywhae
KEGG Pathways K06630 K06630
KOG [O] Multifunctional chaperone (14-3-3 family)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ywhae
Morpholinos ywhae MO1 , ywhae MO2 , ywhae MO3 , ywhae MO4 ywhae MO1 , ywhae MO2 , ywhae MO3 , ywhae MO4 ywhae MO1 , ywhae MO2 , ywhae MO3 , ywhae MO4
ORFs ywhae ORF1 ywhae.S ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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