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XB-GENEPAGE-996985
Gene Symbol:
notum
Gene Name: notum, palmitoleoyl-protein carboxylesterase
Synonyms:
( Gene Function: Pectin acetylesterase and similar proteins Protein Function
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Carboxylesterase that acts as a key negative regulator of the Wnt signaling pathway by specifically mediating depalmitoleoylation of WNT proteins. Serine palmitoleoylation of WNT proteins is required f...[+]
Interactants:
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Diseases: External Links:
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Xenbase Gene ID
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XB-GENE-996986 | XB-GENE-996989 | XB-GENE-17335322 | |||||
Gene Symbol | notum | notum.L | notum.S | Chromosome | Chr10 | chr9_10L | chr9_10S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100145278
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444338
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108702711
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | notum | notum.L | notum.S | |||||
Orthology ![]() |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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Publications | ||||||||
First |
Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation., Dev Cell 2015 ![]() |
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Most Recent |
Establishing embryonic territories in the context of Wnt signaling., Int J Dev Biol 2021 ![]() |
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All | View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 9 terms | 6 terms | 6 terms | |||||
PANTHER | notum | |||||||
KEGG Pathways | K19882 | K19882 | ||||||
KOG |
[M] Pectin acetylesterase and similar proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | notum | |||||||
Antibodies | Notum Ab1 | |||||||
Morpholinos | Notum MO1 | Notum MO2 | ||||||
ORFs | notum.L ORF1 | |||||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



