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Summary Expression Gene Literature (23) GO Terms (11) Nucleotides (203) Proteins (35) Interactants (199) Wiki
XB-GENEPAGE-997996
Gene Symbol: orc1

Gene Name: origin recognition complex subunit 1

Synonyms: ( Add synonyms , Nomenclature history )

Gene Function: Origin recognition complex, subunit 1, and related proteins

Protein Function :
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identi...[+]


Interactants: Loading ...
Disease Ontology: Meier-Gorlin syndrome

OMIM Diseases: MEIER-GORLIN SYNDROME 1; MGORS1

 
Xenbase Gene ID XB-GENE-997997 XB-GENE-998003 XB-GENE-17337988
Gene Symbol orc1 orc1.L orc1.S
Chromosome Chr04 chr4L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.1
CDS Gene model
Entrez Gene: 734048
Entrez Gene: 398063
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine orc1 orc1.L orc1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards ORC1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Orc1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR orc1 ZFIN Ensembl
chicken
GEISHA ORC1 Ensembl
fruit fly
FLYBASE Orc1 Ensembl
worm
WORMBASE
Publications
First Interaction between the origin recognition complex and the replication licensing system in Xenopus., Cell 1996  
Most Recent The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines., Cell Chem Biol 2017                          
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 5 terms 0 term
PANTHER orc1
KEGG Pathways K02603 K02603
KOG [L] Origin recognition complex, subunit 1, and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Horizon Horizon
Antibody Orc1 Ab1 Orc1 Ab1
ORF orc1.L ORF1
Affymetrix 1.0 Str.21585.1.S1_at [+] Xl.371.1.S1_at
Affymetrix 2.0 Xl2.371.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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