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Summary Expression Gene Literature (25) GO Terms (17) Nucleotides (215) Proteins (43) Interactants (205) Wiki
XB-GENEPAGE-997996
Gene Symbol:
orc1

Gene Name:
origin recognition complex subunit 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
Origin recognition complex, subunit 1, and related proteins

Protein Function :
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identi...[+]


InterPro :
Sds3 , Peripla BP I , GPCR 3 Ca sens rcpt-rel , GPCR 3 [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
Meier-Gorlin syndrome

OMIM:
MEIER-GORLIN SYNDROME 1; MGORS1

External Links:
 
Xenbase Gene ID XB-GENE-997997 XB-GENE-998003 XB-GENE-17337988
Gene Symbol orc1 orc1.L orc1.S
Chromosome Chr4 chr4L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 734048
398063
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine orc1 orc1.L orc1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards ORC1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Orc1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Orc1 Ensembl
zebrafish
ZFIN, AGR orc1 ZFIN Ensembl
chicken
GEISHA ORC1 Ensembl
fruit fly
FLYBASE Orc1 Ensembl
Publications
First Interaction between the origin recognition complex and the replication licensing system in Xenopus., Cell 1996  
Most Recent SSRP1-mediated histone H1 eviction promotes replication origin assembly and accelerated development., Nat Commun 2020                  
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 6 terms 0 term
PANTHER orc1
KEGG Pathways K02603 K02603
KOG [L] Origin recognition complex, subunit 1, and related proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks orc1
Antibodies Orc1 Ab1 Orc1 Ab1
ORFs orc1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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