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Summary Expression Gene Literature (95) GO Terms (29) Nucleotides (82) Proteins (35) Interactants (507) Wiki
XB-GENEPAGE-998105
Gene Symbol:
pik3ca

Gene Name:
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

Synonyms:
pi3k , PI3K-alpha , PI3-kinase , pi3-k ( Add synonyms , Nomenclature history )

Gene Function:
phosphoinositide-3-kinase

Protein Function :


InterPro :
Ubiquitin-like domsf , PI3K Vps34 , PI3/4 kinase cat dom , PI3/4 kinase CS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
stomach cancer [+]

OMIM:
GASTRIC CANCER, HEREDITARY DIFFUSE; HDGC [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-998106 XB-GENE-998109 XB-GENE-17344667
Gene Symbol pik3ca pik3ca.L pik3ca.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100144924
373752
108718090
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine pik3ca pik3ca.L pik3ca.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PIK3CA OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Pik3ca MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Pik3ca Ensembl
zebrafish
ZFIN, AGR pik3ca ZFIN Ensembl
chicken
GEISHA PIK3CA Ensembl
fruit fly
worm
Publications
First Embryonic mesoderm cells spread in response to platelet-derived growth factor and signaling by phosphatidylinositol 3-kinase., Proc Natl Acad Sci U S A 1996  
Most Recent A direct role for SNX9 in the biogenesis of filopodia., J Cell Biol 2020                
All View All Papers 5 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 29 terms 0 term 5 terms
PANTHER pik3ca
KEGG Pathways K00922 K00922
KOG [T] Phosphatidylinositol 3-kinase catalytic subunit (p110)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks pik3ca
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info