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Summary Expression Gene Literature (69) GO Terms (21) Nucleotides (204) Proteins (38) Interactants (244) Wiki
XB-GENEPAGE-999034
Gene Symbol:
furin

Gene Name:
furin, paired basic amino acid cleaving enzyme

Synonyms:
PACE , spc1 , xfurin ( Add synonyms , Nomenclature history )

Gene Function:
proprotein convertase

Protein Function :
Ubiquitous endoprotease within constitutive secretory pathways capable of cleavage at the RX(K/R)R consensus motif.



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-999035 XB-GENE-999039 XB-GENE-17342978
Gene Symbol furin furin.L furin.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100327238
398345
397747
mRNA NCBI Nucleotide RefSeq RefSeq
Protein NCBI Protein RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine furin furin.L furin.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FURIN OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Furin MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Furin Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR furinb furina ZFIN Ensembl
chicken
GEISHA FURIN Ensembl
fruit fly
worm
Publications
First Prohormone processing in Xenopus oocytes: characterization of cleavage signals and cleavage enzymes., Proc Natl Acad Sci U S A 1991  
Most Recent Plasmin improves blood-gas barrier function in oedematous lungs by cleaving epithelial sodium channels., Br J Pharmacol 2020  
All View All Papers 3 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 2 terms 8 terms
PANTHER furin
KEGG Pathways K01349 K01349 K01349
KOG [O] Subtilisin-like proprotein convertase (alt_id KOG:3526)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks furin
ORFs furin.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

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