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Summary Expression Gene Literature (14) GO Terms (23) Nucleotides (1208) Proteins (65) Interactants (186) Wiki
XB-GENEPAGE-999730
Gene Symbol:
ddx3x

Gene Name:
DEAD-box helicase 3 X-linked

Synonyms:
An3 ( Add synonyms , Nomenclature history )

Gene Function:
ATP-dependent RNhelicase

Protein Function :
Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo-and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially do...[+]



Interactants:
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Diseases: 


OMIM:
INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED, SYNDROMIC, SNIJDERS BLOK TYPE; MR

External Links:
1/2
 
Xenbase Gene ID XB-GENE-999731 XB-GENE-999738 XB-GENE-17330554
Gene Symbol ddx3x ddx3x.L ddx3x.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394804
379975
397935
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine ddx3x ddx3x.L ddx3x.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards DDX3X OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ddx3x MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ddx3x Ensembl
zebrafish
chicken
GEISHA DDX3X Ensembl
fruit fly
Publications
First The Xenopus localized messenger RNA An3 may encode an ATP-dependent RNA helicase., Nature 1991  
Most Recent The RNA helicase DDX3 induces neural crest by promoting AKT activity., Development 2021  
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 16 terms 4 terms 11 terms
PANTHER ddx3x
KEGG Pathways K11594 K11594 K11594
KOG [A] ATP-dependent RNhelicase (alt_id KOG:0335)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks ddx3x
Morpholinos ddx3x MO2 ddx3x MO2 ddx3x MO2
ORFs ddx3x ORF1 ddx3x.L ORF1 ddx3x.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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