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Summary Expression Gene Literature (13) Interactants (36) Wiki
XB-GENEPAGE-490623

Gene Symbol: brca1

Gene Name: breast cancer 1, early onset

Synonyms: breast and ovarian cancer susceptibility protein Add Xenopus synonyms

Gene Function: zinc finger transcriptional regulator

Interactants: bard1(3) , antxr1(2) , atr(2) , chek1(2) , clspn(2) , mlh1(2) , ran(2) View All
 
  XB-GENE-490624 XB-GENE-6254021  
Molecules tropicalis laevis
Gene JGI XT Genome 4.1 Ensembl
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq
Genomic tropicalis

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Expression tropicalis laevis
UniGene Str.65999 Xl.12105
Gurdon EST/FL CABE7459 XL485j04ex
Affymetrix 1.0 Str.10583.2.S1_at [+] Xl.12105.1.S1_at
GEO data GEO
Orthology MOD Entrez Gene Genetic Phenotypes Morphants
human OMIM:Gene BRCA1
mouse MGI Brca1 All(17) Targeted, knock Out(8) Targeted, other(9)
zebrafish
Publications
First: Swift is a novel BRCT domain coactivator of Smad2 in transforming growth factor beta signaling. [Mol Cell Biol 2001]
Most recent: PIASy mediates SUMO-2/3 conjugation of poly(ADP-ribose) polymerase 1 (PARP1) on mitotic chromosomes. [J Biol Chem 2010]
View All Papers
Functional Ontologies
GO: Molecular: DNA binding
ubiquitin-protein ligase activity
zinc ion binding
      Biological: DNA repair
protein ubiquitination
      Cellular Component: intracellular
nucleus
ubiquitin ligase complex
EC:
KOG: [LK] Transcriptional regulator BRCA1
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