tpx2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (47)

Interactants (34)

XB-GENEPAGE-5810263

[provisional- machine annotated only] Gene Symbol: tpx2 [Predicted: Source is Human Entrez Gene] Gene Name: TPX2, microtubule-associated [Predicted: Source is Human Entrez Gene] Synonyms: dil2, dil-2, hctp4, repp86 Add Xenopus synonyms Gene Function: Interactants: aurka(25) , ran(19) , kif15(8) , aurkb(5) , numa1(4) , tp53(4) , ckap5(3) View All

XB-GENE-5810264

XB-GENE-6251919

XB-GENE-6255926

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 4.1 Ensembl
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001102763\|Xenopus (Silurana) tropicalis TPX2, microtubule-associated (tpx2), mRNA ACGGGTTTCCCTGCAGGTACACACGACTGTGGGACGCTCTAAGGTCGTGGTGCCATGGCAGAAGCGCAGGACCTCTACACATTCGATGCACCTTCCACTTTCATTAACTTTACTGCCTTCCATGAGGATCACGGCGCTGACTCCTGGTTTGACAAAGTGACCAATGCGGAAAATATTCCCCCAGACCAGAGACGGCTCTCTGAGATTCCTGCTGTGAATGCAGAGCAGAATGGCATGGTGGAGCCAGAAGAGACCTCCCCTTCAAAGGAGACAGTTTCTGAGAGTGCTGCACATTTTAGTGATGGGAAATCCCAGGCAAGGCGGTCATCCAGGCGCATGTCTAGGAAGCACCGGCAGAAGCTCCTCGTGAAAATGAGAGAGACGCGCCTGGAGAAAGAGACTGCGCAGTCAGACTGCCCGCCAACCAAGAAACTAAAGGGGTCCAGCACTAAAGGCGCACGTACCCCAGTAATCCGGGGCCAGCCCAGAAGCGGCCATGGCAGCAACACCTCTCCCAGACCAAAAGCTCCACTGACCCTGCCCTCGACTCCGACTGTACTGAAGAGGAAGAATGTAATGGTGAAGCCTAAAAGCTCAGAAGAACAAGAGCTTGAGAGAATGCAAGAACTTCAGAAGGAAATGCTGGAGAATCTAAAGAAAAATGAGCATTCAATGAAAGCTGCCATAAGTGGCACAGGACCCTCAGTGAAGAAGAGTGCCGTACCTATTACAAAACCAGTGGATTTTCACTTTAAAACCGATGACCGGCCCAAGCGGGTTGCTGACCAGCCTAAGGGAGAGGAATATAAAGAGGTGGACTTTGCCGCAGCGTTGAGGAAACACCCACCATCCCCGGTTTCCAAAGCGGCGCTCACAGTCCCTAAACCCTTTAACCTCTCCAAGGGCAAGCGCAAGCACGAGGAGGCCTCAGAGTTTGTCTCCACCGCTGAGCAGGTTATATCCTTCTCCAAGAAAACTCCGGCGCGGTACCATCTGCGCAGCCGCCAGAGGGAGCTAGAGGGCCCCTCCCCAGTGAAGATGGTCCGCCCTAAACTGACCAACCCAAAGACCCCACTGCTCCAAACCAAACAGCGGCTCCGGCCTGTTATGTGTAAAAGTGCCGCAGAGCTGGAAGCAGAGGAACTGGAGAGGATCCAGCAGTACAAGTTTAAGGCTCAGGAACTGGACAGCAGAATCCTAGAAGGGGCTCAAGTTCTCCCTAGGAAGCCCCCCGTTAAGGAACCCACTAAAGCCATTGGCTTTGACTTGGAAATAGAGAAGAGAATCCAGCAGCGGGAGAAGAGAGACGAAGGGGAAGAAGAGGCTTTCACCTTCCATTCTAGACCTTGTCCTTCCAAACTGCTGACAGAGGTGGTGGGCGTCCCCCTTAAGAAGCTGCTCCCAGTGACGGTGCCTCATTCGCCTTCTTTTGCTCTTAAGAACAGAGTGCGCCTCCCAGCGCGGGAAGAGAAGGAAGAGGAGGTGCCGGCTATTAAAGCCACTGCAATGCCCCACTACGGCGTGCCTTTCAGGCCGAAACTGGTACAACAGAGACAAGTTGAAGTCTGTCCTTTTTCATTCTCTGATCAGGACAGAGAGAGACTTCTGCGGAAAGAGAAACGGATGGAGGAACTCCGCAAAGAGGAGGTCCACAAGTTCAAGGCTCAGCCGCTGCCAGAGTTTGGGCATGTCTCTCTGCCTGAAAAGAGGGTGAAGATGCCAACCCAGCAGGAGCCGTTTGTGCTGGAGATTGACAAACGGGGGGCCCCCAGGTTGCAGCGCTGGCAGCAGCAGGTCAAAGAAGAACAAAAGCAGCAGAAAGAAATGGCCGTGTTCAAGGCAAGGCCCAACACTGTGGTCCACCAAGAACCCTTCCTTCCCAAGAAGGAATCCCGTTGCCTCACAGCTACGGAAGGCTTTGAACTGGCCACAGAGAAACGGGCCAAGGAGCGCCAGGAGTTTGAGAAGAGTTTGGCAGAGATGGAGGCTCAAAAGAGCCTTTTGGAAGAGGAAACCCGGCAGCGACAGGAGGAAGAGGAGAGGGAGGAGATCAGTCATCTGAGGAAAGAGCTGGTACACAAAGCGCAGCCAATCAGGAAGTACAAAGCTGTGGATGTGAAAGCCAGTGACACCCCCCTTACCATCCCTGAGTCCCCCAACTTCTCAGACAGGTTCAAATGCTGATGCCCCTGCCAATCTGTTTTTCGGGGGTTGCTGCCCGTTCATGCCCTGGATCATACAGTCTGTTGCACAAACCCATATCCTGTGCATAATGGCATGGACGCAGGGGCGTGTCTCTGGGCAATGGGGGGCGGGGTTTGTAAATTCTAAATCTTGGATGGCTATTATATTAGATGGAGGCGTCTGTTTTTAGGTCTCCCTGTGTAAATATGTATGCTTTTATTCCTTGTAATAAACTTTGTAAAATGTGAAAAAAAAAAAAAAAA	Refseq >NM_001088537\|Xenopus laevis TPX2, microtubule-associated (tpx2), mRNA TTTTGGGTTGAGATTACGCTTCGTAAATTGGGCCGTGCAGAGGAACTAGTTGGATCCAGAAGCCCTTCCACATACTGATTCATAGTGACTGTAGGATATTATAGAAGCCCGTGTCGCCATGGAAGATACACAGGACACCTACAGCTACGACGCCCCTTCTATTTTCAACTTTAGCTCATTTCATGAGGATCACAACGCTGACTCCTGGTTCGACCAAGTGACCAATGCAGAAAATATTCCCCCTGACCAGAGACGGCTCTCTGAGACTTCTGTGAATACTGAGCAAAATTCAAAGGTGGAACCAGTACAGACCACCCCTTCAAAGGATGATGTCTCCAATAGTGCTACACATGTTTGTGATGTGAAATCTCAGTCAAAGAGGTCATCCAGGCGGATGTCTAAGAAGCATCGGCAGAAGCTTCTCGTAAAAATGAAAGACACACACCTGGAAAAAGAGACTGCACCACCGGAATACCCACCGTGCAAAAAATTAAAGGGGTCCAGTTCTAAAGGCAGACATGCTCCAGTAATCAAGAGCCAATCCACAAGCAGCCATCACAGCATGACCTCTCCAAAACCGAAAGCCCAACTGACCATGCCCTCAACTCCAACCGTACTGAAGAGAAGGAATGTGCTTGTAAAGGCTAAAAACTCAGAAGAACAGGAGCTTGAGAAAATGCAAGAACTTCAGAAGGAAATGCTAGAGAATCTCAAGAAAAATGAGCATTCCATGAAAGTTGCCATAACTGGAGCAGGTCAACCAGTGAAGACCTTCATTCCAGTTACAAAACCAGTGGATTTTCACTTTAAAACGGACGACCGTCTCAAGCGCACTGCCAATCAGCCAGAGGGGGATGGCTATAAAGCGGTGGACTTTGCTTCGGAGCTAAGAAAACACCCACCATCACCAGTTCAAGTTACCAAAGGAGGGCACACTGTTCCGAAACCCTTCAACCTGTCCAAGGGCAAACGTAAGCATGAGGAGGCTTCAGATTACGTCTCCACTGCTGAGCAGGTTATTGCCTTCTACAAAAGAACTCCAGCACGTTATCACCTGCGCAGCCGCCAGAGGGAGATGGAGGGACCCTCCCCAGTGAAGATGATCAAAACAAAACTGACCAACCCAAAGACCCCACTGCTCCAAACCAAAGGGCGTCATCGGCCAGTCACGTGTAAAAGTGCTGCAGAGCTGGAAGCTGAGGAACTGGAGATGATAAATCAGTACAAGTTTAAGGCTCAGGAACTGGACACTAGAATCCTGGAAGGGGGTCCAGTCCTCCTTAAGAAGCCCCTTGTTAAGGAACCCACTAAAGCCATTGGTTTTGACTTGGAAATAGAGAAGAGAATCCAACAGCGGGAGAAGAAAGAAGAAATTGAAGAAGAGACTTTCACTTTCCACTCTAGACCTTGCCCTTCCAAAATGCTGACCGATGTGGTGGGTGTCCCGCTGAAGAAGCTGCTCCCAGTGACAGTGCCTCAGTCTCCTGCTTTTGCTCTGAAGAACAGAGTACGCATTCCGGCCCAGGAAGAGAAGCAGGAAGAGATGGTGCCAGTTATCAAAGCCACTCGTATGCCACACTATGGGGTCCCATTCAAGCCCAAGCTCGTAGAACAGCGACAAGTGGACGTTTGTCCCTTTTCCTTTTGTGACAGAGACAAGGAGCGACAACTGCAGAAAGAGAAGCGATTGGATGAACTGCGCAAAGATGAGGTCCCTAAATTCAAGGCTCAGCCGCTACCACAGTTCGATAACATCCGTCTTCCTGAAAAGAAGGTGAAGATGCCGACCCAGCAGGAGCCATTTGACCTCGAGATTGAGAAACGCGGAGCCTCCAAATTGCAGCGGTGGCAGCAGCAGATCCAAGAGGAGCTGAAGCAGCAAAAAGAAATGGTTGTGTTCAAGGCACGGCCCAACACTGTTGTCCACCAAGAACCCTTTGTTCCCAAGAAGGAAAATAGGAGTCTTACAGAGAGCCTTTCTGGTTCCATAGTTCAAGAAGGCTTTGAGCTGGCTACAGCAAAACGGGCCAAAGAGCGCCAGGAGTTTGACAAGTGCTTGGCAGAGACGGAAGCTCAGAAGAGCCTTTTGGAAGAGGAGATTCGAAAGCGACGGGAAGAGGAGGAAAAGGAAGAGATCAGTCAGCTGAGGCAAGAGCTGGTGCACAAGGCCAAGCCTATCAGGAAGTACAGAGCTGTGGAAGTTAAAGCCAGTGACGTCCCACTTACCGTCCCCAGATCCCCCAACTTCTCGGACAGGTTTAAGTGTTGATTCGTTTTCCTGTGTCACAGCCAAAGCCAGTTTTCTGGGTGTGGTTGCCTGTTCATGCCCTGGACCATATAGTCTGTTGAACAAAACTGTGTCCTTTTAAATAGTGGAGTTGACGCAGGGGCAAGTGTCTGCTCATTGGGGTTTTGTAAATACTAGATATTAATGGCCTGGAGGGGCCTGTTTTTAGGTCTTCCATGTGAATACGTTATGCTTTTATTATGCCCTGTAATAAACTGTGTAAATGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGAAAAAAAAAAAAAAAAAGAAAAAAAAAAAAAAAAAAAAAAAAAA		Refseq >NM_001093282\|Xenopus laevis TPX2, microtubule-associated (tpx2-b), mRNA CGTTCTAAGGCCGTGTCGCCATGGCAGACGCGCAGGACACCTACTCCTATGATGCCCCGTCTATTTTCAACTTTAGCTCATTCCATGACGACCACAACGCGGACTCCTGGTTTGACCAATTGACCAATGCAGAAAATATTCCCCCAGACCAGAAACCGCTTTCTGAGACTTCTGTAAATGCTGAGCAGAATTGCAAGGTGGAGCCAGGAAAGATCACCCCTTCAAAGGAGGAAGTCTCAAAGAGTACTACACATGTTTGTGATGTGAAATCTCAGACAAAGCGGTCTGCCAGGCGGATGTCTAAGAAACATCGGCAGAAGATCCTCCTAAAAATGAAGGAGACACATCTGGAAAAAGAGACGGCACAATCTGAATACCCACCATGCAAAAAACTAAAAGGGTCCAGTACTAAAGACAGACAAGCTCCAGTAATCAGGGGCCAACCCACAAGCAGCCATCATGGCACCACCTCTCCAAAACCGAAAGCCCAACTAACCATGCCCGCAACTCCAACTGTGCTGAAGAGGAGGAACATTCTGGCGAAGTCTAAAAGTTCAGAAGAACAAGAGCTTGAGAAAATGCAAGCGCTTCAGAAGGAAATGCTAGAGAATCTCAAGAAAAATGAGCACTCCATGAAAGTTGCCATATCTGGAGCAGGTCAACCAGTGAAGAACTTCATTCCAGTCACAAAACCAGTGGATTTTCACTTTAAAACGGATGATCGACTCAAGCGTAATGCCAATCCGCCTGAGGGAGATGGCTACAAGGAGGTGGACTTTGCTTCGGTGCTAAGGAAACCCCCAACATCACCAGTCCAGGTTACCAAAGGAGGACACACTGTCCCAAAACCCTTCAACCTATCCAAGGGCAAACGAAAACATGAGGAGGCTTCAGACTTTGTCTCCACTGCTGAGCAGGTTGTTGCCTTTTACAGAAGAACTCCAGCACGTTACCACCTGCGCAGCCGCCAGAAGGAGATGGAGGGACCCTCTCCAGTGAAGATGCTCAAACCAAAACTGACCAACCCAAAGACCCCACTGCTCCAAACCAAACAGCGTCATCGGCCAACCACATGTAAAAGTGCTGCAGAGCTGGAAGCTGAGGAACTAGACATGATTCATCAGTACAAGTTTAAGGCTCAGGAGCTGGACACTAGAATCCTGGAAGGGGGTCCAGTCCTCCCTAAGAAGCCCTCTGTCAAGGAACCCACTAAAGCCATTGGTTTTGACTTGGAAATAGAGAAGAGAATCCAGCAGCGGGAGAAGAAAGATGAAGTGGAAGAAGAGGCCTTTTCTTTCCACTCTAGACCTTGCCCTTCCAAAATTCTGGCAGATGTGGTGGGGGTCCCCCAGAAGAAGCTTCTCCCAGTGACTGTGCCTCAGTCTCCTGCTTTTGCTCTGAAGAACAGGGTACGCATTCCGGCACAGGAAGAGAAGGAAGAGGAGGTGCCAGTTATTAAAGCCACTCGAATGCCGCACTACGGGGTCCCATTCAAGCCCAAACTTGTAGAACAGAAACAAGTGGAGGCTTGTCCCTTTTCCTTTTGTGAGCGAGACAAGGAGCGGCAGCTGCAGAAAGAGAAGCGATTGGATGAACTTCGCAAAGAGGAGGTCCCTAAATTCAAAGCTCAGCGGCTGCCACAGTTCGATCACATCAGCCTTCCTGAGAAAAAGGTGAAGATGCCCACCCAGCAGGAGCCATTTCAGCTTGAGATTGACAAACGCGGAGCCACCAAATTGCAGCGCTGGCAGCACCAGATCAAAGAGGAGCTGAAGCAGCAAAAAGAAATGGTTGTGTTTAAGGCGCGGCCCAACACTGTTGTCCACCAAGAACCTTTTGTTCCCAAGAAGGAAAGTAGGAGCCTTACAGATAGCCTTTCTGGTTCCATGATTCAAGAAGGCTTTGAGCTGGCTACAGCAAAAAGGGCCAAGGAGCGCCAGGAGTTTGAGAAGTGCTTGGCAGAGATGGAAGCTCAAAAGAGCCTTTTGGAAGAAGAGACCCGAAAGCAACGGGAAGAGGAAGAAAGGGAAGAGATCAATCAGCTGAGGCAAGAGCTGGTGCATAAGGCACAGCCTATCAGGAAGTTCAAAGCTGTGGAAGTTAAAGCCAGTGACGTCCCACTTACTGTCCCCGCATCCCCTAACTTCTCGGACAGGTTTAAGTGCTGATGTGCTCCCTGTACTAAGCAAATCCAGATTCGGGTAGTGGTTACCTATTCATGCCCTGGACCATACAGTCTATTGTACAAACAAGTGTCCTTAAAATAGTGGCATAAATCAGGGCAAAGATCTGCTCATTCGGGGTGTTATGTAAATACTATATTATATGGCCTGGAGGGGCCTGTTTTTAGGTCTCCCTGTATGCGAATACTTATGCTTTTATTGTGCCCTGTAATAAACTGTGGAAATGTAAAGTTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001096233\|targeting protein for Xklp2 [Xenopus (Silurana) tropicalis] MAEAQDLYTFDAPSTFINFTAFHEDHGADSWFDKVTNAENIPPDQRRLSEIPAVNAEQNGMVEPEETSPSKETVSESAAHFSDGKSQARRSSRRMSRKHRQKLLVKMRETRLEKETAQSDCPPTKKLKGSSTKGARTPVIRGQPRSGHGSNTSPRPKAPLTLPSTPTVLKRKNVMVKPKSSEEQELERMQELQKEMLENLKKNEHSMKAAISGTGPSVKKSAVPITKPVDFHFKTDDRPKRVADQPKGEEYKEVDFAAALRKHPPSPVSKAALTVPKPFNLSKGKRKHEEASEFVSTAEQVISFSKKTPARYHLRSRQRELEGPSPVKMVRPKLTNPKTPLLQTKQRLRPVMCKSAAELEAEELERIQQYKFKAQELDSRILEGAQVLPRKPPVKEPTKAIGFDLEIEKRIQQREKRDEGEEEAFTFHSRPCPSKLLTEVVGVPLKKLLPVTVPHSPSFALKNRVRLPAREEKEEEVPAIKATAMPHYGVPFRPKLVQQRQVEVCPFSFSDQDRERLLRKEKRMEELRKEEVHKFKAQPLPEFGHVSLPEKRVKMPTQQEPFVLEIDKRGAPRLQRWQQQVKEEQKQQKEMAVFKARPNTVVHQEPFLPKKESRCLTATEGFELATEKRAKERQEFEKSLAEMEAQKSLLEEETRQRQEEEEREEISHLRKELVHKAQPIRKYKAVDVKASDTPLTIPESPNFSDRFKC UniProtKB	Refseq >NP_001082006\|targeting protein for Xklp2-A [Xenopus laevis] MEDTQDTYSYDAPSIFNFSSFHEDHNADSWFDQVTNAENIPPDQRRLSETSVNTEQNSKVEPVQTTPSKDDVSNSATHVCDVKSQSKRSSRRMSKKHRQKLLVKMKDTHLEKETAPPEYPPCKKLKGSSSKGRHAPVIKSQSTSSHHSMTSPKPKAQLTMPSTPTVLKRRNVLVKAKNSEEQELEKMQELQKEMLENLKKNEHSMKVAITGAGQPVKTFIPVTKPVDFHFKTDDRLKRTANQPEGDGYKAVDFASELRKHPPSPVQVTKGGHTVPKPFNLSKGKRKHEEASDYVSTAEQVIAFYKRTPARYHLRSRQREMEGPSPVKMIKTKLTNPKTPLLQTKGRHRPVTCKSAAELEAEELEMINQYKFKAQELDTRILEGGPVLLKKPLVKEPTKAIGFDLEIEKRIQQREKKEEIEEETFTFHSRPCPSKMLTDVVGVPLKKLLPVTVPQSPAFALKNRVRIPAQEEKQEEMVPVIKATRMPHYGVPFKPKLVEQRQVDVCPFSFCDRDKERQLQKEKRLDELRKDEVPKFKAQPLPQFDNIRLPEKKVKMPTQQEPFDLEIEKRGASKLQRWQQQIQEELKQQKEMVVFKARPNTVVHQEPFVPKKENRSLTESLSGSIVQEGFELATAKRAKERQEFDKCLAETEAQKSLLEEEIRKRREEEEKEEISQLRQELVHKAKPIRKYRAVEVKASDVPLTVPRSPNFSDRFKC UniProtKB		Refseq >NP_001086751\|targeting protein for Xklp2-B [Xenopus laevis] MADAQDTYSYDAPSIFNFSSFHDDHNADSWFDQLTNAENIPPDQKPLSETSVNAEQNCKVEPGKITPSKEEVSKSTTHVCDVKSQTKRSARRMSKKHRQKILLKMKETHLEKETAQSEYPPCKKLKGSSTKDRQAPVIRGQPTSSHHGTTSPKPKAQLTMPATPTVLKRRNILAKSKSSEEQELEKMQALQKEMLENLKKNEHSMKVAISGAGQPVKNFIPVTKPVDFHFKTDDRLKRNANPPEGDGYKEVDFASVLRKPPTSPVQVTKGGHTVPKPFNLSKGKRKHEEASDFVSTAEQVVAFYRRTPARYHLRSRQKEMEGPSPVKMLKPKLTNPKTPLLQTKQRHRPTTCKSAAELEAEELDMIHQYKFKAQELDTRILEGGPVLPKKPSVKEPTKAIGFDLEIEKRIQQREKKDEVEEEAFSFHSRPCPSKILADVVGVPQKKLLPVTVPQSPAFALKNRVRIPAQEEKEEEVPVIKATRMPHYGVPFKPKLVEQKQVEACPFSFCERDKERQLQKEKRLDELRKEEVPKFKAQRLPQFDHISLPEKKVKMPTQQEPFQLEIDKRGATKLQRWQHQIKEELKQQKEMVVFKARPNTVVHQEPFVPKKESRSLTDSLSGSMIQEGFELATAKRAKERQEFEKCLAEMEAQKSLLEEETRKQREEEEREEINQLRQELVHKAQPIRKFKAVEVKASDVPLTVPASPNFSDRFKC UniProtKB

Genomic

tropicalis

Genome Browser

Synteny

Xenbase G-Browse

GBrowse

Expression		tropicalis	laevis a		laevis b
UniGene		Str.45236	Xl.658		Xl.4592
Gurdon EST/FL		IMAGE:6991244	IMAGE:6637457
Affymetrix 1.0		Str.11137.1.S1_s_at [+] Str.51747.1.A1_at	Xl.658.1.S1_at [+] Xl.658.1.S2_at		Xl.4592.2.A1_at
GEO data			GEO		GEO

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene	TPX2
mouse		MGI	Tpx2
zebrafish

Publications
First:		Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein. [J Cell Biol 1998]
Most recent:		Expression of Targeting Protein for Xenopus Kinesin-like Protein 2 is Associated with Progression of Human Malignant Astrocytoma. [Brain Res 2010]
		View All Papers

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:		[RP] FOG: Immunoglobin and related proteins

Suppliers		tropicalis	laevis a		laevis b
Clones		open biosystems	open biosystems		open biosystems
		geneservice	geneservice		geneservice
		RZPD imagenes	RZPD imagenes		RZPD imagenes

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