Gene Symbol: irf1 Gene Name: interferon regulatory factor 1 Add Xenopus synonyms Gene Function: transcription factor Interactants:

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001006694|Xenopus (Silurana) tropicalis interferon regulatory factor 1 (irf1), mRNA GGGAAACATCTCTCCAGGAATCGCTCGTTTAGGAGATATTTCTGATTCACGTCGCCCCTTTTCTCTCTGGATTACAAATTCCTGCTAGAAAGAAATAATGCCCGTGACACGTTTACGGATGAGGCCATGGCTAGAGGAGCAAATAAACTCCAACAAAATCCCTGGACTTTCATGGATCAACAAGGAAGAAATGATATTTGAGATCCCTTGGAAACACGCTGCTAGACATGGATGGGACATCAATAAAGATGCGTGCCTTTTCCGTAGCTGGGCTGTCCATACAGGACGTATTAAGTCTGGTGAGAAGGAGACAGACCCTAAGACTTGGAAGGCCAATTTCCGCTGTGCAATGAACTCCCTGCCAGATATAAAAGAAGTAAAAGACAAAAGCATATACAAAGGTTCCAGTGCAGTCCGAGTGTATAAAATGCTCCCGCCTCAAATAAAGGCCGAGAAGAAAGAACGCAGATCCAAGGCAAAAGACTCCAAAAGCAAAGCCAAGAAAAAGACTGAGGAAGATGAGGAATCTGTGAAAACTAGCCCTTTGCCTGCAGACCACAGCTACACCTCTAATGTGTATACAGACCAAGAAGACATGGATTCTGTGGATGCGGCTGTAATGAGTATCAATGAAAGTGTCTCTGGCAACTTAGATTGGGACAGTCAACTTCAAATGCCATTGCCTGACAGCACAAATGACCTCTACCCTTTCCAGGTGTCACCCTTAAATTCATCTTCAGAAGAGGAAGATGAATGTATGACCCTTACAGAGGACTTTCTAAAATTGTTAGAGCCAAGCACAGAATGGCAGCAGACAAGCATTGATGGCAAAGGGTTTTTCACCAATGAATCTGGCCTGCAGACCTCCTGCCTTACTGAAATAAGCTCTGCATTCGATGGCACGTTATCGGGCGAAATACAAGTCAGATTCTCCACAGACATGATCAACTGGCCAGAGTCAAGCTTTTCCTCCAGGGCTACTGGGGTAGCTATCTCTACATTCTGAACTTTACCTCCTACCATTCCAAAGCACTTATCATGGAGAACTGACTGGCAGAAGTCCAGTTCTGGGGGAACAGGCAGGACATTATTTGGTCACTACTGCTGGGTTGGCCATTACCGACTGTGAAAAGGAGGACAAGTCATATGTGGACGTCTGATTTGTTACTTTTTTACTCAACACTGAAGCGGAATATATAGCACTACATTGTATATGTGAAAGTCAGCCTGTTCCTACCCTCTGTGACTCATACACTGATAGAACCTATTAGCAATACTGCAATATTTTGTGCACTTAATTTGAAACTTTGCATTGGTATAATGTAAATATATTGATTGTTAGTGGTTTAACATTAGTTCTGCATTCAGCCGTTGCTGACAACTCAAATGCAAATATTCAGGGTTGTTTTGTACTGTAGAAGGAGCACCGCTAAATACGAAACTAAACTCATCTATGCTGGTTATAACATGCAAATACTTTAACAGGTATTGCTGAGCTGCATTTCCAGCATCAAACTGGCCATACAGGGGCTGATATAGTCTCCTGCATCTCTGGATAGGTCTGCACAGGCACTTAATGTGATCCAGTCATAGGCCCAGGGGCCAGATAATTGGATTAGACCGATTTGGCCCACCACCATAGTGGAAAAAGTGTGCAAATATCAGCAAACAAGCAGCTTTTTAGGTGGTATGGCCTGCTGTTTACTTGTAAATGATTACATTTTGGGCAGCTATCATTCTTCACTTAACGTGTAATAGGATAACAAAAAATAATTTCAGTATTTCTAAAATAAGGTTCTATGCAGAAGTTTTACCATAAATATGCTGTTACTTCATTATGAGGTATTTGTAAATAGTATATTTGTATAAAAATGTTTAAATAAATTCTGTTTATATAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001089781|Xenopus laevis interferon regulatory factor 1 (irf1), mRNA GGAATCATCTCTCCAGGAATCGTTCACTTAGGAGCTATAGCTTCCTCCCAACATTCCTCTTTTCTCTCTGGATTACAAATTCCTGCTGGAAAGAAATAATGCCTGTGACACGTTTAAGGATGAGGCCATGGCTAGAGGAGCAGATAAACTCCAACAAAATCCCTGGATTGTCATGGATCAACAAGGATAAAATGATATTCCAGATCCCTTGGAAACATGCTGCTAGACATGGATGGGACATCAATAAAGATGCCTGCCTTTTCCGGAGTTGGGCTGTCCATACAGGACGTTTTAAATCTGGCGAGAAGGAGACCGACCCTAAAACTTGGAAGGCCAATTTCCGATGCGCAATGAACTCTCTGCCGGATATAAAAGAAGTCAAAGACAAAAGCATATACAAAGGCTCCAGTGCAGTGCGAGTATATCAGATGTTCACACCTCAAATAAAGGCTGAGAAGAAAGAGCGCAGATCCAAGGCAAAATGCTCTAAAAGCAAAGCCAAGTATAAGACTGAGGAAGACGAGGAATCTGTAAAAACTAGCCCATTGCCTGTAGACCACAGCTACACTGCTAATGTATATACAGACCAAGAAGACATGGATTCTGTGGATGCAGCTGTAATGAGCCTCAACGAAAGTGTCTCTAGCACCTTGGACTGGGACTCTCAACTTGAAATGCCATTGCCTGACAGCACAAATAACCTCTACCCTTTCCAGGTGTCACCCTTGAGTTCATCTTCGGAAGAGGAAGAAGACTTTCCAGACGACTTTCTTAGGATGATGTTAGAGCCAAGCACAGAATGGCAGCAGACAAGCATAGATGGCAAAGGGTTTTTCACCAATGAATCTGGTATGCAGAACGCCTGTCTAACTGAAATAAGCTCTGCATTCGACGGCACGTTATCAGGTGAAATAAAAGTCAGATTCTCCACAGACTTGATCAACTGGCCCGACTATTCCTCAAGGGCTACAGGATTAGCTGTCCCCACTTTTTGAACTTTACCTCCTATCATTCCAAAGCACTTACATGGATTCAGCAAAGAGCACTGACTAGCGTAAGGCCAGTTTTGGGGGAACAGACAGGACAATGCTTGGTCGCTACTGCTGGGATGGCCATCGCCGACTGTGAAAATAAGGAGGACAAGTCATATGTGGACGTTTGATTTGCTCAACCCTGAAGCATGAAAAATAGCACTACATTGCATATGTGAAAGTGAATCTGTTCCTACCCTCTGTGACTGTGTACAATCAGAGAACCTATTTGCAATACTGCATTGTTGTGTGCACTTGTTTAGAAACCTTCTATTGGTATCATGTAAATATATTGAATATTAGTGGTTTACGTTTAGTTCTTTATTCAGCCGTTGCCATCTGTAGGGGCTTCTCCTGTGGCACTGGCTGAGAGAAGGCTTTTTGTGAAAAAAAGTCTAATACAGCTCTCTAAACTAAAATGCAAATATTTAAGATCGTTTTGTACTGTAGAATGGACACCTGTAAAGCCATATTAATAAAACATCTACACTGGTGATAACATGCAACTTACTTCCTAGGGATTGCTGAACCCTAGGGTTCATACAAAGGATTATGGAGTGTCCAGCATCTGTGCATCGGTTTGCACAGGCCCTTAATGTGATCCAATCGTTGGCCCAGCAGCAAAATGATCGGATTTAGCCCGTCACCTTAATGGAAAAATTGTGCAAATCTCATCAAACCGTTAGATTTTTAGATACTTTGACCAGTTTGCCACTCGTTTGCTAAGGAATCCATGTTTTTGTAAAAGATTAAATTTTGGACAACTATCATGCTTCACGATATGTGTAATAAATAGGATTAAAAAAGAAATAAGTCATTTCAACAGTATTTTCGAAATACGGTTCTGTGCAGAGGTTCCACCTTAAACATGCTGTTACGCATTATGAGGTATTTGTAAATAGTACATTTGTATAAACATGTATAATAGTTTGAATAAATTCTGTTTATATATAAAAAAAAAAAAAAA
Protein		Refseq >NP_001006695|interferon regulatory factor 1 [Xenopus (Silurana) tropicalis] MPVTRLRMRPWLEEQINSNKIPGLSWINKEEMIFEIPWKHAARHGWDINKDACLFRSWAVHTGRIKSGEKETDPKTWKANFRCAMNSLPDIKEVKDKSIYKGSSAVRVYKMLPPQIKAEKKERRSKAKDSKSKAKKKTEEDEESVKTSPLPADHSYTSNVYTDQEDMDSVDAAVMSINESVSGNLDWDSQLQMPLPDSTNDLYPFQVSPLNSSSEEEDECMTLTEDFLKLLEPSTEWQQTSIDGKGFFTNESGLQTSCLTEISSAFDGTLSGEIQVRFSTDMINWPESSFSSRATGVAISTF	Refseq >NP_001083250|interferon regulatory factor 1 [Xenopus laevis] MPVTRLRMRPWLEEQINSNKIPGLSWINKDKMIFQIPWKHAARHGWDINKDACLFRSWAVHTGRFKSGEKETDPKTWKANFRCAMNSLPDIKEVKDKSIYKGSSAVRVYQMFTPQIKAEKKERRSKAKCSKSKAKYKTEEDEESVKTSPLPVDHSYTANVYTDQEDMDSVDAAVMSLNESVSSTLDWDSQLEMPLPDSTNNLYPFQVSPLSSSSEEEEDFPDDFLRMMLEPSTEWQQTSIDGKGFFTNESGMQNACLTEISSAFDGTLSGEIKVRFSTDLINWPDYSSRATGLAVPTF

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.4753 [+] Str.33217	Xl.1419
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	IRF1	OMIM:137215 OMIM:153550
mouse		MGI	Irf1	All(5) Targeted, knock Out(3) Targeted, other(1) Chemically Induced(1)
zebrafish		ZFIN ZFIN	irf1a irf1b	2 Lines(s)

Publications
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Most recent:
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Functional Ontologies
GO: Molecular:		transcription factor activity
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.4753.1.S1_at [+] Str.33217.1.A1_at	Xl.1419.1.A1_at
Affymetrix 2.0			Xl2.1419.1.S1_s_at

Symbol legend[+]

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