Gene Symbol: lmna Gene Name: lamin A/C Synonyms: Lamin-A, lamin a Add Xenopus synonyms Gene Function: nucleoskeletal protein Interactants: lmnb3(8) , lmnb1(7) , lmnb2(4) , igf2bp3(3) , emd(2) , robo3(2) , vim(2) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001045683|Xenopus (Silurana) tropicalis lamin A/C (lmna), mRNA AGCAGATCCCTGCGCACTGACAGCCCCCCGTGTATTCGCCAAGAGCCATGGAGACCCCCGGGCAGAAGCGGGCGACCCGCAGCACCCACACCCCACTCTCCCCCACCCGCATCACCCGCCTGCAGGAGAAGGAAGACCTGCAGGAACTCAACGACCGATTGGCCGTCTACATCGACAAGGTGCGCTCCTTGGAGTCGGAGAACGCCGGGCTGCGCCTGCGCATCACTGAGTCCGAAGAGGTGGTCAGTCGCGAGGTGTCGGGCATCAAGGGGGCCTACGAGGCGGAACTGGCGGACGCCCGCAAAACTCTCGACTCGGTGGCCAAGGAGAGGGCTCGCCTGCAGCTGGAGCTCAGCAAGATCCGCGAGGAGCACAAGGAGCTGAAAGCGAGGAACGCCAAGAAGGAGAGCGATCTGCTGACGGCGCAGGCGCGGCTGAAGGATTTGGAGGCCCTGCTGAACTCTAAAGATGCCGCCCTCACCACGGCGCTGGGAGAGAAGAGGAATCTGGAGAACGAGATCAGGGAACTTAAGGCTCACATTGCAAAGTTGGAGGCCAGCCTCGCCGACACAAAGAAACAACTGCAGGACGAGATGCTCCGCCGCGTGGATACCGAGAACCGCAACCAGACGCTGAAGGAGGAGCTTGAGTTCCAGAAGAACATTTCTAACGAGGAGATGCGCGAGACCAAGCGCCGCCACGAGACCCGGATGGTGGAGATGGACAACGGGCGGCAGAGGGAGTTTGAGTCCAAACTGGCGGACGCCCTGCAGGATCTCCGTGCCCAACACGAGGGGCAGGTCGGCCTCTACAAGGAAGAGCTGGAGAAGACCTACAATGCCAAGCTGGAGAATGCCAAGCAGTCGGCCGAGAGGAACAGCAGCCTGGTGGGAGAAGCCCAGGAGGAGATTCAGCAGAGCCGGATCCGCATCGACAGTCTCTCTGCCCAGCTCAGCCAACTGCAGAAACAGCTGGCGGCTAAAGAGGCCAAACTACGGGATCTGGAGGACGCCTACGCCCGCGAACGGGACTCCAACCGGCGCCTCATGTCGGACAAGGACCGGGAGATGGCGGAGATGCGGGCCCGTATGCAGCAGCAGCTGGACGAGTACCAGGAACTGCTGGACATCAAACTGGCGCTGGACATGGAGATCCATGCCTACCGCAAACTACTGGAGGGAGAGGAGGAGAGGCTGCGTCTCTCCCCCAGTCCTACCACTCAGAAGAGGTCGGCAAGGACCGTCGCCTCCCACTCTGGGACCCACATCTCCTCCTCTGCCTCCAAGAGGCGGCGCCTAGAGGCCGGGGAGTCGGGGAGCACCAGTTACACCCAACACGCCCGCACCACCGGGAAGGTCTCCGTGGAAGAGGTGGATCCGGAGGGGAAATACGTGCGGCTGCGGAACAAGAGTAACGAGGACCAATCGCTGGGGAACTGGCAGATCAAGCGCCAGATAGGGGAGGAGACCCCCATTGTGTACAGGTTCCCCCCCAGACTTACACTAAAGGCCGGACAAACGGTGACGATCTGGGCATCAGGCGCCGGAGCCACAAATAACCCCCCCACTGATTTAGTATGGAAGGCCCAGAGCTCCTGGGGAACAGGCGACAGTATTCGCACCGCGCTGCTCACGTCTAACAATGAGGAGGTTGCTATGAGGAAACTGGTGCGCACTGTCGTCATCAATGATGAAGATGGAGATGATGAAGATGATGACGATGTGGGACATCACCACCACCACCACCATCATCATCATCATGATGGGCAGAATAGCGGGGACCCCGGGGAGTACAATCTGCGCTCTCGCACCATCGTTTGCACCAGCTGTGGGCGCCCGGCTGAGAAGGGGGTTCTAGGCTCCCAGGGTTCTGGTTTGGCCACGGCCTCGACCGGTTCCTCATCCTCCAGCGTCACCCTGACCCGGACCTACCGCAGCACCGGGGGAACCAGCGGGGGCAGTGCCCTCGGGGAGAGTCTGGTCACCAGGACCTACATTGTCGGGAACGACAGCCAGCGTGCCCAGGTCACCCCGCAGAGCTGCAGCATAATGTAATCCGCTGCCCGACGCCGCCGTCACCAAGTGCCCAAGTGCCCGAGCGAAACAGAGAGATTTTGGTTTTTTTATGAAAATTTTGTTTTTATTTTATACTGCGAGAATTTTATAAAAAAAAAAAAAAAAAA	Refseq >NM_001101740|Xenopus laevis lamin A/C (lmna), mRNA CCAAGCTATGGAGACCCCAGGTCAGAAGCGGGCGACCCGCAGCACCCACACCCCACTCTCCCCCACCCGTATCACCCGCCTGCAGGAGAAGGAAGATCTGCAGGGGCTCAATGACCGATTGGCCGTCTACATCGACAAGGTGCGTTCCCTGGAGCTGGAGAACGCCCGGCTGCGTCTGCGAATCACCGAGTCTGAAGACGTCATCAGCCGCGAGGTCACGGGCATCAAGTCAGCGTATGAGACGGAGCTGGCGGACGCACGGAAAACTCTGGACTCGGTGGCCAAGGAGAGGGCTCGTCTGCAGCTGGAGCTGAGCAAGATCCGCGAGGAGCACAAGGAGCTGAAAGCGAGGAATGCCAAGAAAGAGAGCGATCTATTGACAGCGCAGGCCAGACTGAAGGATTTGGAGGCCCTGTTGAACTCTAAAGATGCCGCCCTCACCACAGCGCTGGGAGAGAAGAGGAATCTGGAGAATGAGATCAGGGAACTTAAGGCTCACATTGCAAAGTTGGAGGCCAGCCTCGCCGACACAAAGAAACAACTGCAGGACGAGATGCTCCGTCGTGTGGATACTGAGAACCGTAACCAGACGCTGAAGGAGGAACTTGAGTTCCAAAAGAGCATTTACAACGAGGAGATGCGGGAGACTAAACGCCGCCATGAGACCCGACTGGTGGAGGTCGACAACGGGCGCCAGAGGGAGTTTGAGTCTAAATTGGCTGATGCCCTTCATGAGTTGCGTGCCCAACATGAGGGGCAGATAGGCCTGTACAAGGAAGAGCTGGGGAAGACTTACAATGCCAAGCTGGAGAATGCCAAGCAGTCGGCGGAGAGGAACAGCAGTCTGGTGGGAGAAGCTCAGGAGGAGATTCAGCAGAGCAGGATCCGCATCGACAGTCTCTCGGCCCAGCTCAGCCAACTGCAGAAACAGCTGGCGGCCAGAGAGGCCAAACTTCGGGATCTGGAGGACGCCTATGCGCGTGAACGGGACTCCAGCCGCCGGCTCCTGGCAGACAAGGACCGGGAGATGGCGGAAATGAGGGCCCGCATGCAACAACAGCTGGACGAGTACCAGGAGCTGCTGGACATTAAACTGGCTCTGGACATGGAGATCAACGCCTACCGCAAGTTACTGGAGGGAGAGGAGGAGAGGCTGCGTCTCTCCCCCAGTCCCAACACCCAGAAGAGGTCGGCCCGGACCATCGCCTCTCACTCGGGGGCCCACATCTCCTCCTCGGCCTCCAAGAGACGTCGCCTGGAAGAAGGGGAATCGCGGAGCAGCAGCTTCACCCAACACGCCCGCACCACCGGGAAAGTGTCAGTGGAAGAGGTGGATCCCGAGGGGAAATATGTCCGACTGAGGAACAAGAGTAATGAGGACCAATCGCTGGGGAACTGGCAGATCAAGCGTCAGATCGGGGACGAGACCCCCATTGTGTACAAGTTCCCTCCCAGACTTACACTAAAGGCCGGACAAACCGTAACGATTTGGGCATCAGGAGCTGGAGCCACAAATAGTCCCCCCAGTGATTTAGTGTGGAAGGCCCAGAGCTCTTGGGGAACAGGCGACAGTATTCGCACAGCTCTGCTCACATCAAGCAATGAGGAAGTTGCTATGAGGAAACTGGTGCGAACTGTGGTCATCAATGATGAAGATGATGAAGATAATGATGATATGGAACATCACCACCACCATCATCATCATCATCATGATGGGCAGAACTCTAGTGGAGACCCTGGGGAGTACAACCTGCGCTCTCGCACTATCGTTTGCACCAGCTGTGGGCGCCCAGCTGAGAAGAGTGTCCTGGCCTCCCAGGGTTCTGGGTTGGTCACTGGATCATCAGGTTCTTCTTCCTCCAGCGTCACCCTTACTCGGACCTACCGTAGCACAGGGGGAACCAGCGGGGGCAGTGGCCTCGGGGAGAGTCCGGTCACCAGGAACTTCATTGTTGGAAATGGCCAACGTGCCCAGGTCGCCCCGCAGAACTGCAGTATAATGTAACCGGATGCCACCACTGTTCTTATCACCAAGTGCCCAAGCTAAAGAGAATTTTTTGTTTTTTTAATGTATTTTATTTTTTTTTTATACTGCAAGAATTTTATAAAGG
Protein		Refseq >NP_001039148|lamin A/C [Xenopus (Silurana) tropicalis] METPGQKRATRSTHTPLSPTRITRLQEKEDLQELNDRLAVYIDKVRSLESENAGLRLRITESEEVVSREVSGIKGAYEAELADARKTLDSVAKERARLQLELSKIREEHKELKARNAKKESDLLTAQARLKDLEALLNSKDAALTTALGEKRNLENEIRELKAHIAKLEASLADTKKQLQDEMLRRVDTENRNQTLKEELEFQKNISNEEMRETKRRHETRMVEMDNGRQREFESKLADALQDLRAQHEGQVGLYKEELEKTYNAKLENAKQSAERNSSLVGEAQEEIQQSRIRIDSLSAQLSQLQKQLAAKEAKLRDLEDAYARERDSNRRLMSDKDREMAEMRARMQQQLDEYQELLDIKLALDMEIHAYRKLLEGEEERLRLSPSPTTQKRSARTVASHSGTHISSSASKRRRLEAGESGSTSYTQHARTTGKVSVEEVDPEGKYVRLRNKSNEDQSLGNWQIKRQIGEETPIVYRFPPRLTLKAGQTVTIWASGAGATNNPPTDLVWKAQSSWGTGDSIRTALLTSNNEEVAMRKLVRTVVINDEDGDDEDDDDVGHHHHHHHHHHHDGQNSGDPGEYNLRSRTIVCTSCGRPAEKGVLGSQGSGLATASTGSSSSSVTLTRTYRSTGGTSGGSALGESLVTRTYIVGNDSQRAQVTPQSCSIM	Refseq >NP_001095210|lamin-A [Xenopus laevis] METPGQKRATRSTHTPLSPTRITRLQEKEDLQGLNDRLAVYIDKVRSLELENARLRLRITESEDVISREVTGIKSAYETELADARKTLDSVAKERARLQLELSKIREEHKELKARNAKKESDLLTAQARLKDLEALLNSKDAALTTALGEKRNLENEIRELKAHIAKLEASLADTKKQLQDEMLRRVDTENRNQTLKEELEFQKSIYNEEMRETKRRHETRLVEVDNGRQREFESKLADALHELRAQHEGQIGLYKEELGKTYNAKLENAKQSAERNSSLVGEAQEEIQQSRIRIDSLSAQLSQLQKQLAAREAKLRDLEDAYARERDSSRRLLADKDREMAEMRARMQQQLDEYQELLDIKLALDMEINAYRKLLEGEEERLRLSPSPNTQKRSARTIASHSGAHISSSASKRRRLEEGESRSSSFTQHARTTGKVSVEEVDPEGKYVRLRNKSNEDQSLGNWQIKRQIGDETPIVYKFPPRLTLKAGQTVTIWASGAGATNSPPSDLVWKAQSSWGTGDSIRTALLTSSNEEVAMRKLVRTVVINDEDDEDNDDMEHHHHHHHHHHDGQNSSGDPGEYNLRSRTIVCTSCGRPAEKSVLASQGSGLVTGSSGSSSSSVTLTRTYRSTGGTSGGSGLGESPVTRNFIVGNGQRAQVAPQNCSIM UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.37520	Xl.1237 [+] Xl.60118
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	LMNA	OMIM:115200 OMIM:151660 OMIM:607920 OMIM:605588 OMIM:181350 OMIM:604929 OMIM:176670 OMIM:608056 OMIM:248370 OMIM:159001 OMIM:275210 OMIM:277700 OMIM:611618
mouse		MGI	Lmna	All(18) Targeted, knock Out(6) Targeted, other(8) Spontaneous(1)
zebrafish		ZFIN	lmna

Publications
First:		Differential expression of nuclear lamin proteins during chicken development. [J Cell Biol 1987]
Most recent:		The nucleoporin Nup88 is interacting with nuclear lamin A. [Mol Biol Cell 2013]
		View All Papers

Functional Ontologies
GO: Molecular:		structural molecule activity
Biological:
Cellular Component:
EC:
KOG:		[DY] Nuclear envelope protein lamin, intermediate filament superfamily

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.37520.1.S1_at	Xl.1237.1.S1_at
Affymetrix 2.0			Xl2.1237.1.S1_at

Symbol legend[+]

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   - Literature Or Expression Images