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Summary Expression Gene Literature (11) GO Terms (22) Nucleotides (178) Proteins (37) Interactants (81) Wiki
XB-GENEPAGE-1001915
Gene Symbol:
ago2

Gene Name:
argonaute 2, RISC catalytic component

Synonyms:
Argonaute2 , argonaute 2 , eif2c2 ( Add synonyms , Nomenclature history )

Gene Function:
translation initiation factor

Protein Function :
Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short in...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1001916 XB-GENE-1001922 XB-GENE-17346099
Gene Symbol ago2 ago2.L ago2.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.1
CDS Gene model Gene model
Entrez Gene 448205
446823
mRNA RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine ago2 ago2.L ago2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards AGO2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Ago2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Ago2 Ensembl
zebrafish
ago2 Ensembl
chicken
GEISHA AGO2 Ensembl
fruit fly
FLYBASE AGO2 Ensembl
worm
Publications
First Co-expression of Argonaute2 Enhances Short Hairpin RNA-induced RNA Interference in Xenopus CNS Neurons In Vivo., Front Neurosci 2009              
Most Recent MicroRNP-mediated translational activation of nonadenylated mRNAs in a mammalian cell-free system., Genes Cells 2018              
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 22 terms 17 terms 0 term
PANTHER ago2
KEGG Pathways K11593 K11593
KOG [J] Translation initiation factor 2C (eIF-2C) and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks ago2
ORFs ago2.L ORF1
Clones Horizon Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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