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Summary Expression Gene Literature (1) GO Terms (7) Nucleotides (92) Proteins (24) Interactants (47) Wiki
XB-GENEPAGE-1003599
Gene Symbol: top3a

Gene Name: DNA topoisomerase III alpha

Synonyms: xtop3a ( Add synonyms , Nomenclature history )

Gene Function: DNA topological change

Protein Function :
Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription b...[+]

Interactants: Loading ...
Diseases:  OMIM: MICROCEPHALY, GROWTH RESTRICTION, AND INCREASED SISTER CHROMATID EXCHANGE 2; MGR [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
 
Xenbase Gene ID XB-GENE-1003600 XB-GENE-1003603 XB-GENE-17340766
Gene Symbol top3a top3a.L top3a.S
Chromosome Chr09 chr9_10L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100135734
444125
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL RefSeq TrEMBL TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine top3a top3a.L top3a.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TOP3A OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Top3a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR top3a ZFIN Ensembl
chicken
GEISHA TOP3A Ensembl
fruit fly
worm
WORMBASE
Publications
First FANCD2 regulates BLM complex functions independently of FANCI to promote replication fork recovery., Nucleic Acids Res 2013                    
Most Recent
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 5 terms 0 term
PANTHER top3a
KEGG Pathways K03165
KOG [L] DNA topoisomerase III alpha
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks top3a
ORFs top3a.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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