Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (1) GO Terms (6) Nucleotides (179) Proteins (43) Interactants (535) Wiki
XB-GENEPAGE-1008757
Gene Symbol:
thap1

Gene Name:
THAP domain containing, apoptosis associated protein 1

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modul...[+]


InterPro :
Rab-GTPase-TBC dom , EF hand dom , Rab-GTPase TBC sf , EF Hand 1 Ca BS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
torsion dystonia 6

OMIM:
DYSTONIA 6, TORSION; DYT6

External Links:
 
Xenbase Gene ID XB-GENE-1008758 XB-GENE-1008764 XB-GENE-17330728
Gene Symbol thap1 thap1.L thap1.S
Chromosome Chr01 chr1L Scaffold21
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448407
495360
446612
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot RefSeq
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine thap1 thap1.L thap1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards THAP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Thap1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Thap1 Ensembl
zebrafish
ZFIN, AGR thap1 ZFIN Ensembl
chicken
GEISHA THAP1 Ensembl
fruit fly
worm
Publications
First Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions., Int J Dev Biol 2014                  
Most Recent
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 6 terms 4 terms
PANTHER thap1
KEGG Pathways K23203 K23203 K23203
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks thap1
ORFs thap1 ORF1 thap1.L ORF1 MGC82205 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556