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Summary Expression Gene Literature (21) GO Terms (18) Nucleotides (134) Proteins (33) Interactants (159) Wiki
XB-GENEPAGE-1009778
Gene Symbol:
lig1

Gene Name:
ligase I, DNA, ATP-dependent

Synonyms:
ligI , ligase I , DNA ligase I ( Add synonyms , Nomenclature history )

Gene Function:
DNA replication and base excision repair

Protein Function :
DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-1009779 XB-GENE-1009783 XB-GENE-17337412
Gene Symbol lig1 lig1.L lig1.S
Chromosome Chr7 chr7L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100271763
397978
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lig1 lig1.L lig1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LIG1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lig1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lig1 Ensembl
zebrafish
ZFIN, AGR lig1 ZFIN Ensembl
chicken
GEISHA LIG1 Ensembl
fruit fly
worm
Publications
First DNA ligase I from Xenopus laevis eggs., Nucleic Acids Res 1991  
Most Recent Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder., Med Sci Monit 2016  
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 11 terms 0 term
PANTHER lig1
KEGG Pathways K10747
KOG [L] ATP-dependent DNA ligase I
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lig1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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