Due to necessary maintenance, Xenbase will be unavailable from December 24-29, 2014. We apologize for the inconvenience.

Click on this message to dismiss it.
Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (11) Nucleotides (113) Proteins (21) Interactants (70) Wiki
XB-GENEPAGE-1009778

Gene Symbol: lig1

Gene Name: ligase I, DNA, ATP-dependent

Synonyms: ligI, ligase I, DNA ligase I Add Xenopus synonyms

Gene Function: DNA replication and base excision repair

Interactants: Flrt3 Ab1(1) , Tuba4b Ab4(1) , act3(1) , anxa1(1) , aqp3(1) , bhmt(1) , ccnb1.2(1) View All

Disease Associations:
 
  XB-GENE-1009779 XB-GENE-1009783
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein Refseq UniProtKB
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
tropicalis 4.1 synteny
Expression tropicalis laevis
UniGene Str.54355 Xl.78 [+]
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 6 expression image(s) for tropicalis and laevis
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC LIG1
mouse
MGI Lig1 All
zebrafish
chicken
Publications
First: DNA ligase I from Xenopus laevis eggs. [Nucleic Acids Res 1991]
Most recent: Genome-wide expression profile of the response to spinal cord injury in Xenopus laevis reveals extensive differences between regenerative and non-regenerative stages. [Neural Dev 2014]
View All Papers
Functional Ontologies
GO: Molecular: ATP binding
DNA ligase (ATP) activity
      Biological: DNA recombination
DNA repair
DNA replication
      Cellular Component:
EC: DNA ligase (ATP)
KOG: [L] ATP-dependent DNA ligase I
Reagents tropicalis laevis
CRISPR / TALEN Design E-CRISP / Other tools
Design E-CRISP / Other tools
Clones
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody
Morpholino
Affymetrix 1.0 Str.20174.1.S1_a_at [+] Xl.78.1.S1_at [+]
Affymetrix 2.0 Xl2.78.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [3.3]


Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556