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Summary Expression Gene Literature (9) Nucleotides (112) Proteins (21) Interactants (9) Wiki
XB-GENEPAGE-1009778

Gene Symbol: lig1

Gene Name: ligase I, DNA, ATP-dependent

Synonyms: ligI, ligase I, DNA ligase I Add Xenopus synonyms

Gene Function: DNA replication and base excision repair

Interactants: ccnb1.2(1) , cdk1(1) , cdkn1a(1) , cdt1(1) , ddb1(1) , dtl(1) , fen1(1) View All
 
  XB-GENE-1009779 XB-GENE-1009783  
Molecules tropicalis laevis
Gene JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1 JGI XL Genome 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq UniProtKB
Genomic tropicalis
Genome Browser GBrowse
Xenbase
GBrowse
Xenbase JGI Ensembl UCSC
GBrowse
Xenbase
Synteny Metazome
Expression tropicalis laevis
UniGene Str.54355 Xl.78 [+]
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 6 expression image(s) for tropicalis and laevis
Orthology MOD Entrez Gene Genetic Phenotypes Morphants
human OMIM:Gene, HGNC LIG1
mouse MGI Lig1 All(4) Targeted, knock Out(2) Targeted, other(2)
zebrafish
Publications
First: DNA ligase I from Xenopus laevis eggs. [Nucleic Acids Res 1991]
Most recent: Positively charged residues located downstream of PIP box, together with TD amino acids within PIP box, are important for CRL4(Cdt2) -mediated proteolysis. [Genes Cells 2011]
View All Papers
Functional Ontologies
GO: Molecular: ATP binding
DNA ligase (ATP) activity
      Biological: DNA recombination
DNA repair
DNA replication
      Cellular Component:
EC: DNA ligase (ATP)
KOG: [L] ATP-dependent DNA ligase I
Reagents tropicalis laevis
Clones open biosystems open biosystems
geneservice/RZPD imagenes geneservice/RZPD imagenes
Affymetrix 1.0 Str.20174.1.S1_a_at [+] Xl.78.1.S1_at [+]
Affymetrix 2.0 Xl2.78.1.S1_at [+]

Symbol legend[+]