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Summary Expression Gene Literature (41) GO Terms (19) Nucleotides (267) Proteins (52) Interactants (532) Wiki
XB-GENEPAGE-1011480
Gene Symbol:
mcm4

Gene Name:
minichromosome maintenance complex component 4

Synonyms:
cdc21 , mcm4-a , mcm4-b ( Add synonyms , Nomenclature history )

Gene Function:
DNA replication licensing factor, MCM4 component

Protein Function :
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The a...[+]



Interactants:
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Diseases: 


OMIM:
IMMUNODEFICIENCY 54; IMD54

External Links:
 
Xenbase Gene ID XB-GENE-1011481 XB-GENE-1011486 XB-GENE-6252896
Gene Symbol mcm4 mcm4.L mcm4.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448137
397843
373601
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine mcm4 mcm4.L mcm4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards MCM4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Mcm4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Mcm4 Ensembl
zebrafish
ZFIN, AGR mcm4 ZFIN Ensembl
chicken
GEISHA MCM4 Ensembl
fruit fly
worm
Publications
First Fission yeast cdc21+ belongs to a family of proteins involved in an early step of chromosome replication., Nucleic Acids Res 1992  
Most Recent TRAIP is a master regulator of DNA interstrand crosslink repair., Nature 2019                            
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 18 terms 12 terms 12 terms
PANTHER mcm4
KEGG Pathways K02212 K02212 K02212
KOG [L] DNA replication licensing factor, MCM4 component
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks mcm4
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

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