[provisional- machine annotated only] Gene Symbol: gad1.1 [Predicted: Source is Human Entrez Gene] Gene Name: glutamate decarboxylase 1 (brain, 67kDa), gene 1 [Predicted: Source is Human Entrez Gene] Synonyms: gad67, cpsq1 Add Xenopus synonyms Gene Function: Glutamate decarboxylase and related proteins Interactants: calb1(1) , dlx2(1) , emx1(1) , emx1.2(1) , gad2(1) , gpsm1(1) , pcp4(1) View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		NCBI Nucleotide >XM_002934611|PREDICTED: Xenopus (Silurana) tropicalis glutamate decarboxylase 1-like (LOC100496528), mRNA CTGGCCTCATTAGAAGGTTGAGGTAGGGAGCTAAGATATCCATCTGACCTATTGTTTGAACCCCTGACCATGCTCAGGAAAGAGAATACCCTGCCAATGACTTGTTCTCATTGTAACGACGTAGGCTTCCTGCAGAGAAATAACAGTTTGGATGACAAGAGCAGGATTGTGAGTTCCTTCAAAGAGAGGCAAGCTTCCAAAAACCTCCTGGTGTGTGAAAATATCGAGAAAGACTCCCAGTTCCGCCGTGCCGAGACAGACTTCTCCAATCTCTTTGCCAGAGATTTACTGCCTGCTAAGAATGGGGAAGAGTTCACTATGCAGTTCCTGCTGGAGGTGGTTGACATTCTCCTAAACTACGTCAGGAAAACGTTTGATAGATCCACCAAGGTCCTAGACTTTCATCATCCTCACCAGCTTTTAGAGGGCATTGAGGGCTTCAACCTGGAGCTGTCTGACAACCCAGAGTCCTTGGAGCAAATCTTGGTGGACTGTAGGGATACCCTGAAGTATGGAGTTAGAACAGGGCACCCTCGCTTCTTCAACCAGCTCTCAACAGGACTGGATATTATTGGCTTGGCTGGGGAATGGCTGACATCTACCGCTAACACTAACATGTTTACGTATGAGATCGCACCAGTTTTCGTCCTCATGGAACAGATTACGCTTCGGAAAATGAGAGAAATAATCGGCTGGACAGAAAAGGATGGAGATGGAATATTTTCTCCAGGTGGTGCCATCTCCAACATGTACAGCATTATGGCTGCCCGCTACAAATACTTTCCTGAAGTAAAAACCAAAGGCATGGCAGCAGTCCCCAGATTGGTTCTCTTTACCTCAGAACATAGCCACTACTCCATAAAGAAAACTGGGGCTGCGTTGGGGTTCGGAAGTGAAAATGTGATCATGGTAAAGACCAATGAAAGGGGGAAGATAATTCCTGCTGATTTGGAAGCGAAAATCCTCGAAGCAAAACAAAAGGGTTACGTTCCACTGTATGTAAATGCTACCGCTGGGACAACTGTCTATGGTGCGTTTGATCCAATATCTGAGATAGCTGATATCTGTGAAAAATACAACCTCTGGCTTCATGTTGACGCTGCGTGGGGAGGTGGACTGCTCATGTCCAGAAGGCACCGGCATAAATTAGATGGAATAGAGAGGGCTAATTCTGTCACTTGGAATCCTCATAAGATGATGGGTGTCTTACTCCAATGTTCTGCAATTCTTTTAAGAGAAAAGGGCATCCTACAAGGTTGCAATCAGATGTGCGCTGGGTACCTGTTCCAACAAGACAAGCAATATGATATATCATATGACACAGGAGACAAAGCAATACAGTGTGGGCGCCATGTAGACATATTCAAGTTCTGGCTGATGTGGAAAGCCAAGGGCACTGTTGGATTTGAAGCTCAGATCAACAAGTGCTTGGAGCTTGCAGAATATCTCTATTCTAAGATCTACAATCGGGAAGGCTTTGAAATGGTCTTCAATGGAGTGCCTGAGCATACAAATGTCTGTTTCTGGTACATCCCTCCGAGCCTTAGGGGAATGCCCAACAATGAAGAAAAGCAGGAGAAGCTGCACAGGGTGGCTCCTAAAATTAAGGCTCTGATGATGGAATCTGGTACAACGATGGTGGGATACCAGCCACAAGGAGATAAAGCCAATTTCTTCCGAATGGTCATCTCAAACCCAGCAGCGACCAAGTCCGACATCGACTTTCTTGTCGAAGAAATTGAAAGATTGGGTCAGGAATTGTAATAGTTGTGTTGTCTGCCATAAACCCCCAAGGTGCTGGTGGACCTTCCCAAACACTGAGGGGGGGTTAGCTTTTAGTGTTCTATTGCTGGATAAACCACTTGAGAAAAAAATATGGGTTGTGCAATGTACAGAGTCAAGTTTTAAGGACATTTCCTTAATACTTGCGCAATTCCCTTCTAGCACCTTAATTCATTTAGGCTGCTGGAACATCTATGTAGATCATAAACAAAGACTATATTAACTAATGTGTAAGATGAACCTTATTTTTAACCTTCTGAATGCCAATGTGTCTTGGCGGCGCATCTCGCAGCAGGGCGTTGCACTACCCACTGGCTTTCAAAGGCTTAGCAATCTAAATTTTACTTAAGGTAACTGAATGTTGTACAGTGTAACTGTATGTATGTATGTGTGTGTGTGCGCGCGTGTGTGTAAATATAATATATATGTACAGGGTATAGGCAAGTTACGCAGTTGTCAAGAGCAGCAAATGTTGGCGGCACAGTATTGAGAATCATGGGTTTAAGGGTGTGGAAAGTGTGTCCCAATCAATAATCTCTAGGTGAGGCCTCTCGCACACAAAGTTTTAGCTGACAAAAGGTATATTCCTATGTGTAATAAAACAGTCCTTTTGTTCATTATAAATCTACGCACCATCAATAACTTGTGAGATCTCCTATTAGCTATACAATCCCACCATGCCTTCAATTTGTACCGACTTTGCCTCATAATATCCACAACCAATCACTGATTCATCCTAACTGTAGCACATGCAGGAGTCTCTGCCAAATGATACTGGAAGCCTTACTGGGGTAAACATGGTGTATGTGTTGAGTTGGGGTGTGATGTCTTGGCTTTGGGGTGAAGAATGGGAGACTATTCCCTCATATTAGGAAGCATCCCCACAAAGTAGGCCTCATAGACCTGTGAACTTTTTCCATACATAAACAGTGACATGTGACTTTCTGCACAAATGTTTGTGGGTTTCTGGCACTATATAGAAATCCTATATACTAGCAGTAGACCCTGATGTTGGTGCTTTTATCAATAGCCTAACAAGCCTGAAAAGCATTACCCGTAAGTAGATGCACCTCCTGGATGGGGGCAATAGTAGCACAGTCATTGTTACAGGTATATTATCGCTGTATTCTTAGGGATTTATTTGTGTAGAGTGTGTACATTATTGTCGAATAACTTTGTGAAACCAGAATACACGTCATAGTTTTACAGTAAACTGTTATACGATAGGTATATAAAATACTTGCTTATTTATATGCAAAGATTTACCATGTTACAGAGGTGTCTTGTATTTTCTTCCATTTGTATTGTATTCTATTTATATATAATATATATACATAGTATATATTACTGAAGTAAGTTATAAATAATAATTATTGTATTTAAGTGTCTTTGTGAGCCAAAGAAAAACTAAAAAATATAGTAGAAATTGTAGACATGAATATAGTGCCCTCAACATTTATTCCATAAAATATAGAAGAAAATAAGTCCAGAACACAGAACGCTGAGGGTGTTATGGGATTGGCCCAGTGCAGGGTTTGTTTAGCAAGTGTGAGTGGTGCCAACATTCTGCCATGTACTGTAAGAATGAATCACATATTGGAACTTCACAGCACAAAGTTGGTGTTAGTCACTTCTTGCAAGGAACCCCTGTGCTCCTTCCAACCATAAAGTGACCCTACTGTGTTTAGATTCAGACGTGAAGATGGGAGTTATACTATGGTTCAACTTCCTGTGCCCTGAACAGCATATGCCAGTGGTTTAGCTAGGTGCAACAAACTGTCTTTAGCTCAGGGGTCTCCAACTTCATTTACCTGTGGTCCAGACTCAAATGTAAGAAGTGTTGGGAAGCCACACAACCATGAAAAAAAAAGTTCATTGGCATTGCCAACCTGAAAGATTTTTTGCTTGGAGCAAACTTGTATCTTATTGTGGTACAACTTGCCTCCATGCTAGCAATGTAAAAACGAGAACCTGCTTTGAGGCCAGTGAGAGCAGCATCAAAGGGGGTGGAGAACCTCAACTGTCTGTTGAGGTTCAATGTTTTATCTTTTAGAAAATGTACAAGTAGCACCTCTCTTTTGTAGAGATTCCTCTTAATTTCGCAAAATTTCATTTAGAATTGGGCAGAACATTGTTCA	Refseq >NM_001085801|Xenopus laevis glutamate decarboxylase 1 (brain, 67kDa) (gad1), mRNA GGAGAAGATTGTAGTAGGGAGCTAAACTATCCATTTGATCTACTGCTTGAAAGCCTGACCATGCTTAGGAAAGAGAACACCCTGCCAATGACTTGTTCTCATTGCAACAATGTAGGCTTTCTGCAGAGGAATAACAGTTTGGATGACAAGAGCAGGATTGTGAGTTCCTTCAAAGAGAGGCAAGCTTCCAAAAATCTCTTGGTATGTGAAAATATTGAGAAGGATTCCCGGTTTGGCCGTGCTGAGACAGACTTCTCCAATCTCTTTGCTAGAGATTTACTGCCTGCTAAGAATGGGAAGAATTCACAATGCAGTTCCTACTGGAGGTGGTTGACATTCTTTTATACTATGTATGAAAAACATTTGATAGATCCACCAAAGTCCTACACTTTCACCATCCTCACCAACTTCTTGAAGGTATTGAAGGCTTCAACCTGGAGCTGTCTGAAAACCCAGAGTCCTTGGAGCAAATCTTGGTGGATTGTAGGGATACCCTCAAGTATGGAGTCAGAACAGGACATCCTCGCTTCTTCAACCAGCTCTCAACAGGATTGGATATCATTGGCTTGGCTGGGGAATGGCTCACATCAACTGCTAACACTAACATGTTTGTATGAGATCGCCCCAGTTTTCGTACTCATGGAACAGATTACGCTTCGGAAAATGAGAGAAATAATCGGCTGGACAGAAAAAGATGGAGATGGAATATTTTCTCCAGGTGGTGCCATCTCCAACATGTACAGCATTATGGCTGCCCGCTACAAATACTTTCCTGAAGTTAAAACCAAAGGCATGGCAGCAGTCCCCAGATTGGTCCTGTTTACTTCAGAACACAGCCACTATTCCATAAAGAAAACTGGCGCGGCATTAGGATTTGGAAGTGAAAATGTGATCCTTATAAAGAGCGACGAAAGGGGGAAGATGATTCCTGCTGATTTGGAAGCAAAAATCCTTGAAGCAAAGCAAAAGGGTTATATTCCTCTATATGTAAATGCTACAGCTGGGACAACAGTCTACGGTGCTTTTGATCCAATATCTGAGATAGCTGATATCTGTGAAAAATACAATCTCTGGCTACATGTTGATGCTGCATGGGGAGGTGGATTGCTCATGTCCAGAAGGCACCGGCATAAATTAAATGGAATAGAAAGGGCTAATTCTGTCACTTGGAATCCTCATAAGATGATGGGCGTCTTACTCCAATGTTCTGCAATTCTCTTAAGAGAAAAGGGCATACTACAAGGTTGCAATCAGATGTGTGCAGGGTACCTGTTCCAACAAGACAAGCAATATGACGTATCATATGACACAGGAGACAAAGCGATACAGTGTGGTCGCCATGTAGACATATTCAAGTTCTGGCTGATATGGAAAGCCAAGGGCACTGTTGGATTTGAAGCTCAGATCAACAAGTGCTTGGAGCTTGGAGAATATCTATACTCTAAGATCTACAATCGACAAGGCTATGAAATGGTCTTTAATGGAGAGCCTGAGCATACAAACATCTGTTTCTGGTACATCCCTCCAAGTCTTAGGGGAATACCCAACAGTCAAGAAAGGCAGGAGAAACTGCACAGGGTTGCTCCTAAAATCAAGGCTCTAATGATGGAATCTGGAACAACGATGGTGGGATACCAGCCACATGGAGATAAAGTCAATTTCTTCCGAATGGTCATCTCAAACCCAGCAGCGACCAAGTCCGACATCGACTTTCTTGTTGAAGAAATTGAAAGATTGGGTCAGGATTTGTAATAGCTGTGTTGTGAGCCATAAACATCCAATGTGCTGGTGGAACTTCCCAAACACTTGGGGGGATTAAAAAATATGGGTTGTGCAATGTACAGAGTCACGTTTTAAGGGCATTTCCTTAACACTTGCACAATTCCCTTCTAGCACCTTAAATAACTTAGGCTGCTGGAATATGTATGTAGATCATAAACAAATAGTATATTAACTCATGTTTAAGATGAACCTTAAATAAGTATTTTTTGACCTTCTGAAGGCCAATGTGTCTTGACAACACATCTCACAGCAGTGTGTTGCACTACCCATTGGCTTTCAAAGGCTTAGCAATCTACATTATAATTAAGGAAACTGTTGTACAATGTAACTGTATGTATGTATGTGTGTGTATGCGTGTGTGTGTAAATATAATATATATGTACAGGGTAAAGGCAAGTAATGCAGTTGTCTAAAGCGAAACTGTTCCACAGTATTCAGAATAATGTATTCAAAGGTATTGAAAGTGTGTTCCAAACAATAATTTTTAGGTAAGGTCTCTCACACACCAAGTTTTAGCTGACAAATGGTAGATTCTGTGGAGCAGTCTTTCTGTTCATTTAAGACATACACACCATCAACAAAAGCTTATATATCCACAATCAAAGATTTATCCTAACTGTAGAACATGCAAGAGTCTCTGCTAAATGATACTGGAAGCCTTACTGGGGTAAACACGGGTGGATGTATTGGGTTGGGGGTGTGATCCCCTCATAATAGGGAGCATCCCAGTAAGAAGGCCTCATAGGCATTTGTCAAGTTTCATACATAAACAGAGACAACGGACTATCTGCACAAATGTTTGTGGGTTTCTGGCACTATACTGTATATAAATTCTATATACTAGTAGTAGACCCCGATGTTGGTGATTTATCAATAGCATAACAAGCGTGAAAAAGCATTACCCAGTAAATAGATGTGCCTCCTGGAAGTAGTAGCACAGTCATTGTTACAGGTATATATCACTGTGTTTTTAGGGATTTGTTTCGTGTAGAGTGTGTACCTTATTGTTGAACAACTTTGTGAATACTCGTCCTAGTTTTACAGTAACCTGTTATATGATAGATATATGAAATACTTGCTTATTTATATGCAAAGATTTACCGTGTTAAAGAGGTTGCTTGTATTTCTTCCATTGTATTGTACCCTATTTATATATATATATAATATATATACATAGTATATATTACTGAAGTAAGTTATAAATAATGATTATTGTATTCAAGTGTCTTTGTGAGCCAAAGAAAATCTAAAAATATAGTAGAAATTGTAGATATGAATATAGTGCCATCCACAGTAATATATATAAGTATAAAGTCCAGAACACAGAATGCTGAAGGTGTTATGGGATTGGTCCAGAACACAGAATGCTGAAGGTGTTATGGGATTGGTCCAGTGCAGGGTTTGTTTAGCAAGTGCAA
Protein		NCBI Protein >XP_002934657|PREDICTED: glutamate decarboxylase 1-like [Xenopus (Silurana) tropicalis] MLRKENTLPMTCSHCNDVGFLQRNNSLDDKSRIVSSFKERQASKNLLVCENIEKDSQFRRAETDFSNLFARDLLPAKNGEEFTMQFLLEVVDILLNYVRKTFDRSTKVLDFHHPHQLLEGIEGFNLELSDNPESLEQILVDCRDTLKYGVRTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLRKMREIIGWTEKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPRLVLFTSEHSHYSIKKTGAALGFGSENVIMVKTNERGKIIPADLEAKILEAKQKGYVPLYVNATAGTTVYGAFDPISEIADICEKYNLWLHVDAAWGGGLLMSRRHRHKLDGIERANSVTWNPHKMMGVLLQCSAILLREKGILQGCNQMCAGYLFQQDKQYDISYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFEAQINKCLELAEYLYSKIYNREGFEMVFNGVPEHTNVCFWYIPPSLRGMPNNEEKQEKLHRVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAATKSDIDFLVEEIERLGQEL	Refseq >NP_001079270|glutamate decarboxylase 1 [Xenopus laevis] MLRKENTLPMTCSHCNNVGFLQRNNSLDDKSRIVSSFKERQASKNLLVCENIEKDSRFGRAETDFSNLFARDLLPAKNGKNSQCSSYWRWLTFFYTMYEKHLIDPPKSYTFTILTNFLKVLKASTWSCLKTQSPWSKSWWIVGIPSSMESEQDILASSTSSQQDWISLAWLGNGSHQLLTLTCLYEIAPVFVLMEQITLRKMREIIGWTEKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPRLVLFTSEHSHYSIKKTGAALGFGSENVILIKSDERGKMIPADLEAKILEAKQKGYIPLYVNATAGTTVYGAFDPISEIADICEKYNLWLHVDAAWGGGLLMSRRHRHKLNGIERANSVTWNPHKMMGVLLQCSAILLREKGILQGCNQMCAGYLFQQDKQYDVSYDTGDKAIQCGRHVDIFKFWLIWKAKGTVGFEAQINKCLELGEYLYSKIYNRQGYEMVFNGEPEHTNICFWYIPPSLRGIPNSQERQEKLHRVAPKIKALMMESGTTMVGYQPHGDKVNFFRMVISNPAATKSDIDFLVEEIERLGQDL

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		[+] Str.38334	Xl.1029
Unigene EST Profile			EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	GAD1	OMIM:603513
mouse		MGI	Gad1	All(15) Targeted, knock Out(3) Targeted, other(11)
zebrafish		ZFIN	gad1b	2 Lines(s)

Publications
First:		Expression of the genes GAD67 and Distal-less-4 in the forebrain of Xenopus laevis confirms a common pattern in tetrapods. [J Comp Neurol 2003]
Most recent:		Embryonically expressed GABA and glutamate drive electrical activity regulating neurotransmitter specification. [J Neurosci 2008]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		carboxy-lyase activity glutamate decarboxylase activity
Biological:		amino acid metabolic process
Cellular Component:
EC:		glutamate decarboxylase
KOG:		[E] Glutamate decarboxylase and related proteins

Reagents		tropicalis	laevis
Clones			open biosystems
			geneservice/RZPD imagenes
Affymetrix 1.0		Str.38334.1.A1_at	Xl.1029.1.S1_at
Affymetrix 2.0			Xl2.1029.1.S1_at

Symbol legend[+]

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   - Literature Or Expression Images