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Summary Expression Gene Literature (4) Nucleotides (98) Proteins (26) Interactants (6) Wiki

Gene Symbol: apex2

Gene Name: APEX nuclease (apurinic/apyrimidinic endonuclease) 2

Synonyms: ape2, xth2, apexl2 Add Xenopus synonyms

Gene Function: DNA repair

Interactants: atm(1) , atr(1) , atrip(1) , chek1(1) , clspn(1) , mapt(1) , rpa1(1) View All

Disease Associations:
  XB-GENE-1012054 XB-GENE-1012061
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq
Genomic tropicalis laevis
Genome Browser
tropicalis genome v8.0 gene model
laevis genome v7.2 gene model
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene Str.3624 [+] Xl.6497
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 7 expression image(s) for tropicalis and laevis
Phenotype tropicalis laevis
Smith Morpholino Screen    
MOD Entrez Gene Genetic Phenotypes Morphants
MGI Apex2 All available mutants
ZFIN apex2
First: Subtraction scanning acoustic microscopy reveals motility domains in cells in vitro. [Cell Motil Cytoskeleton 1994]
Most recent: APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress. [Proc Natl Acad Sci U S A 2013]
View All Papers
Functional Ontologies
GO: Molecular: DNA-(apurinic or apyrimidinic site) lyase activity
endonuclease activity
nuclease activity
      Biological: DNA repair
      Cellular Component:
EC: DNA-(apurinic or apyrimidinic site) lyase
KOG: [L] Apurinic/apyrimidinic endonuclease and related enzymes
Reagents tropicalis laevis
CRISPR / TALEN Design E-CRISP / Other tools
Design E-CRISP / Other tools
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Affymetrix 1.0 Str.3624.1.S1_at [+] Xl.24861.1.A1_s_at
Affymetrix 2.0 Xl2.6497.1.S1_at

Symbol legend[+]

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