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Summary Expression Gene Literature (4) Nucleotides (98) Proteins (26) Interactants (6) Wiki
XB-GENEPAGE-1012053

Gene Symbol: apex2

Gene Name: APEX nuclease (apurinic/apyrimidinic endonuclease) 2

Synonyms: ape2, xth2, apexl2 Add Xenopus synonyms

Gene Function: DNA repair

Interactants: atm(1) , atr(1) , atrip(1) , chek1(1) , clspn(1) , mapt(1) , rpa1(1) View All

Disease Associations:
 
  XB-GENE-1012054 XB-GENE-1012061
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
tropicalis 4.1 synteny
Expression tropicalis laevis
UniGene Str.3624 [+] Xl.6497
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 7 expression image(s) for tropicalis and laevis
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
APEX2
mouse
MGI Apex2 All
zebrafish
ZFIN apex2
chicken
Publications
First: Subtraction scanning acoustic microscopy reveals motility domains in cells in vitro. [Cell Motil Cytoskeleton 1994]
Most recent: APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress. [Proc Natl Acad Sci U S A 2013]
View All Papers
Functional Ontologies
GO: Molecular: DNA-(apurinic or apyrimidinic site) lyase activity
endonuclease activity
nuclease activity
More[+]
      Biological: DNA repair
      Cellular Component:
EC: DNA-(apurinic or apyrimidinic site) lyase
KOG: [L] Apurinic/apyrimidinic endonuclease and related enzymes
Reagents tropicalis laevis
CRISPR / TALEN Design E-CRISP / Other tools
Design E-CRISP / Other tools
Clones
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
Antibody
Morpholino
Affymetrix 1.0 Str.3624.1.S1_at [+] Xl.24861.1.A1_s_at
Affymetrix 2.0 Xl2.6497.1.S1_at

Symbol legend[+]

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