Xenbase is experiencing difficulties due to technical problems with the University of Calgary IT infrastructure and may go temporarily offline.

Click on this message to dismiss it.
Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (5) Nucleotides (95) Proteins (24) Interactants (14) Wiki
XB-GENEPAGE-1015903

Gene Symbol: cdc23

Gene Name: cell division cycle 23

Synonyms:
Add Xenopus synonyms , Nomenclature history

Gene Function: Anaphase-promoting complex (APC), Cdc23 subunit

Interactants: cdc27(4) , cdc16(3) , ccnb1.2(2) , cdc20(1) , cdc45(1) , fbxo43(1) , fbxo5(1) View All

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-1015904 XB-GENE-1015909 XB-GENE-17341490
Gene Symbol cdc23 cdc23.L cdc23.S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.8410 Xl.2742 Xl.64544
RNA-seq profile: Owens, Blitz et al. 2016 cdc23
Images 0 expression image(s) for tropicalis and laevis
Data Mining
XenMine cdc23 cdc23.L cdc23.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CDC23 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Cdc23 MGI, IMPC Ensembl, Eurexpress, MGI
zebrafish
ZFIN cdc23 ZFIN Ensembl
chicken
GEISHA CDC23 Ensembl
fruit fly
FLYBASE Cdc23 Ensembl
worm
WORMBASE
Publications
First: TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast. [Mol Biol Cell 1996]
Most recent: Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail. [Mol Biol Cell 2010]
View All Papers
Functional Ontologies
GO: Molecular: PANTHER
      Biological: regulation of mitotic metaphase/anaphase transition   PANTHER
      Cellular Component: anaphase-promoting complex   PANTHER
EC:
KOG: [DO] Anaphase-promoting complex (APC), Cdc23 subunit
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
ORF cdc23 ORF1
Affymetrix 1.0 Str.8410.1.S1_at [+] Xl.2742.1.A1_s_at [+]
Affymetrix 2.0 Xl2.2742.1.S1_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [3.11.2]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556