Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (5) Nucleotides (92) Proteins (22) Interactants (13) Wiki
XB-GENEPAGE-1015903

[provisional- machine annotated only]
Gene Symbol: cdc23 [Predicted: Source is Human Entrez Gene]

Gene Name: cell division cycle 23 [Predicted: Source is Human Entrez Gene]

Add Xenopus synonyms

Gene Function: Anaphase-promoting complex (APC), Cdc23 subunit

Interactants: cdc27(4) , cdc16(3) , ccnb1.2(2) , cdc20(1) , cdc45(1) , fbxo43(1) , fbxo5(1) View All

Disease Associations:
 
Xenbase Gene ID XB-GENE-1015904 XB-GENE-1015909
Current JGI Annotation cdc23 cdc23.L
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Refseq
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene Str.8410 Xl.2742
Unigene EST Profile EST Profile EST Profile
GEO data GEO
Images 0 expression image(s) for tropicalis and laevis
Phenotype tropicalis laevis
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC CDC23
mouse
MGI Cdc23 All available mutants
zebrafish
ZFIN cdc23 All
chicken
Publications
First: TPR proteins required for anaphase progression mediate ubiquitination of mitotic B-type cyclins in yeast. [Mol Biol Cell 1996]
Most recent: Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail. [Mol Biol Cell 2010]
View All Papers
Functional Ontologies
GO: Molecular:
      Biological: regulation of mitotic metaphase/anaphase transition
      Cellular Component: anaphase-promoting complex
EC:
KOG: [DO] Anaphase-promoting complex (APC), Cdc23 subunit
Reagents tropicalis laevis
CRISPR / TALEN CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes geneservice/RZPD imagenes
ORF cdc23 ORF1
Affymetrix 1.0 Str.8410.1.S1_at [+] Xl.2742.1.A1_s_at [+]
Affymetrix 2.0 Xl2.2742.1.S1_at

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [3.5.2]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556