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Summary Expression Gene Literature (182) GO Terms (9) Nucleotides (55) Proteins (21) Interactants (406) Wiki
XB-GENEPAGE-1020975
Gene Symbol:
stat3.2

Gene Name:
signal transducer and activator of transcription 3, gene 2

Synonyms:
aprf , hies ( Add synonyms , Nomenclature history )

Gene Function:
signal transduction

Protein Function :
Transcription factor that binds to target promoter sequences and activates transcription upon il6st/gp130 stimulation. Mediates ventralization of embryos, at least in part via inhibition of smad2 signa...[+]



Interactants:
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Diseases: 


Disease Ontology:
T-cell large granular lymphocyte leukemia [+]

OMIM:
HYPER-IgE RECURRENT INFECTION SYNDROME, AUTOSOMAL DOMINANT [+]

External Links:
1/2
 
Xenbase Gene ID XB-GENE-1020976 XB-GENE-1020979 XB-GENE-17344188
Gene Symbol stat3.2 stat3.2.L stat3.2.S
Chromosome Chr10 chr9_10L
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2
CDS Gene model Gene model
Entrez Gene 100498547
379264
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine stat3.2 stat3.2.L stat3.2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards STAT3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Stat3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Stat3 Ensembl
zebrafish
ZFIN, AGR stat3 ZFIN Ensembl
chicken
GEISHA STAT3 Ensembl
fruit fly
worm
Publications
First Activation of Stat3 by cytokine receptor gp130 ventralizes Xenopus embryos independent of BMP-4., Dev Biol 1999                
Most Recent Stable intronic sequence RNAs (sisRNAs) are selected regions in introns with distinct properties., BMC Genomics 2020                                  
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 0 term 9 terms 0 term
PANTHER stat3.2
KEGG Pathways K04692
KOG [KT] STAprotein
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks stat3.2
Clones Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list