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Summary Expression Gene Literature (7) GO Terms (4) Nucleotides (149) Proteins (43) Interactants (580) Wiki
XB-GENEPAGE-1216188
Gene Symbol:
sp8

Gene Name:
Sp8 transcription factor

Synonyms:
btd ( Add synonyms , Nomenclature history )

Gene Function:
zinc finger, C2H2 type

Protein Function :
Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos.



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-1216189 XB-GENE-1216193 XB-GENE-17341049
Gene Symbol sp8 sp8.L sp8.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100492429
495143
108719921
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine sp8 sp8.L sp8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SP8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sp8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sp8 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR sp8a sp8b ZFIN Ensembl
chicken
GEISHA SP8 Ensembl
fruit fly
worm
Publications
First Genomic profiling of mixer and Sox17beta targets during Xenopus endoderm development., Dev Dyn 2006                          
Most Recent A molecular atlas of the developing ectoderm defines neural, neural crest, placode, and nonneural progenitor identity in vertebrates., PLoS Biol 2017                                                
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 2 terms 4 terms 1 terms
PANTHER sp8
KEGG Pathways K09198 K09198 K09198
KOG [R] FOG: Zn-finger
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks sp8
Morpholinos (on-target & off-target) sp8 MO2 , sp8 MO1 sp8 MO1 , sp8 MO2
ORFs sp8.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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