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Summary Expression Gene Literature (49) GO Terms (57) Nucleotides (132) Proteins (25) Interactants (648) Wiki
XB-GENEPAGE-487419

Gene Symbol: smo

Gene Name: smoothened, frizzled class receptor

Synonyms: XSmo , X-smoothened , smoothened ( Add Xenopus synonyms , Nomenclature history )

Gene Function: hedgehog signal transduction

Protein Function :

Interactants: Loading ...
Disease Ontology: basal cell carcinoma

OMIM Diseases: BASAL CELL CARCINOMA, SUSCEPTIBILITY TO, 1; BCC1 [+]

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Xenbase Gene ID XB-GENE-487420 XB-GENE-487424 XB-GENE-17333650
Gene Symbol smo smo.L smo.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq Refseq
Protein NCBI Protein TrEMBL Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine smo smo.L smo.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SMO OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Smo MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR smo ZFIN Ensembl
chicken
GEISHA SMO Ensembl
fruit fly
FLYBASE smo Ensembl
worm
WORMBASE
Publications
First The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants., Development 1998  
Most Recent Structural Basis of Smoothened Activation in Hedgehog Signaling., Cell 2018  
All View All Papers 8 paper(s) referencing morpholinos 49 paper(s) referencing OMIMs 49 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 55 terms 5 terms 6 terms
PANTHER smo
KEGG Pathways K06226 K06226
KOG [T] Smoothened and related G-protein-coupled receptors
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s) EXRC - 1 clone(s)  
GE Dharmacon GE Dharmacon GE Dharmacon
Antibody Smo Ab1 Smo Ab1
Morpholino smo MO1 smo MO1 smo MO1
Affymetrix 1.0 Xl.15716.1.A1_at [+] Xl.760.1.S1_at
Affymetrix 2.0 Xl2.7834.2.S1_at [+] Xl2.760.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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Version: 4.11.1


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