Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (2) GO Terms (12) Nucleotides (94) Proteins (33) Interactants (109) Wiki
XB-GENEPAGE-969638
Gene Symbol:
serpine1

Gene Name:
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Synonyms:
PAI 1 ( Add synonyms , Nomenclature history )

Gene Function:
Serpin

Protein Function :
E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chain...[+]


InterPro :
Serpin sf 1 , Serpin CS , Serpin fam , Serpin sf [+]

Interactants:
Loading ...

Diseases: 


OMIM:
PLASMINOGEN ACTIVATOR INHIBITOR-1 DEFICIENCY

External Links:
 
Xenbase Gene ID XB-GENE-969639 XB-GENE-969642 XB-GENE-17342203
Gene Symbol serpine1 serpine1.L serpine1.S
Chromosome Chr3 chr3L Scaffold20
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100127732
779433
100049768
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine serpine1 serpine1.L serpine1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SERPINE1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Serpine1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Serpine1 Ensembl
zebrafish
ZFIN, AGR serpine1 ZFIN Ensembl
chicken
fruit fly
worm
Publications
First Identification of novel genes affecting mesoderm formation and morphogenesis through an enhanced large scale functional screen in Xenopus., Mech Dev 2005                                                                                                                        
Most Recent Macroarray-based analysis of tail regeneration in Xenopus laevis larvae., Dev Dyn 2005                            
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 1 terms 0 term
PANTHER serpine1
KEGG Pathways K03982 K03982
KOG [V] Serpin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks serpine1
ORFs serpine1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info