Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (58) GO Terms (11) Nucleotides (177) Proteins (52) Interactants (236) Wiki
XB-GENEPAGE-479190
Gene Symbol:
bmp1

Gene Name:
bone morphogenetic protein 1

Synonyms:
xtld , tld , tolloid , bmp-1 , xbmp1 , bmp1-a , bmp1-b ( Add synonyms , Nomenclature history )

Gene Function:
metallopeptidase

Protein Function :
Metalloprotease involved in pattern formation in gastrula and later differentiation of developing organs. Able to cleave chordin (chrd), suggesting that it may act in dorsoventral patterning during ear...[+]


InterPro :
FN3 dom , Ig-like fold , FN3 sf , MetalloPept cat dom sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
osteogenesis imperfecta type 13

OMIM:
OSTEOGENESIS IMPERFECTA, TYPE XIII; OI13

External Links:
 
Xenbase Gene ID XB-GENE-479191 XB-GENE-6252324 XB-GENE-479195
Gene Symbol bmp1 bmp1.L bmp1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 733960
397872
399093
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine bmp1 bmp1.L bmp1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BMP1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Bmp1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Bmp1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR bmp1a bmp1b ZFIN Ensembl
chicken
GEISHA BMP1 Ensembl
fruit fly
worm
Publications
First The astacin family of metalloendopeptidases., J Biol Chem 1991  
Most Recent The ion channel function of polycystin-1 in the polycystin-1/polycystin-2 complex., EMBO Rep 2019                    
All View All Papers 12 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 3 terms 10 terms
PANTHER bmp1
KEGG Pathways K05502 K05502 K05502
KOG [O] Meprin A metalloprotease
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks bmp1
Morpholinos bmp1 MO1 bmp1 MO1 bmp1 MO1
ORFs bmp1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556