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Summary Expression Gene Literature (15) GO Terms (13) Nucleotides (110) Proteins (36) Interactants (731) Wiki
XB-GENEPAGE-479254
Gene Symbol: fgfr3

Gene Name: fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism)

Synonyms: ach , cek2 , jtk4 , cd333 , hsfgfr3ex , fgfr-3 ( Add synonyms , Nomenclature history )

Gene Function: receptor tyrosine kinase

Protein Function :
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an ess...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: LADD syndrome [+]

OMIM: ACHONDROPLASIA; ACH [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
 
Xenbase Gene ID XB-GENE-479255 XB-GENE-479259 XB-GENE-17330101
Gene Symbol fgfr3 fgfr3.L fgfr3.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100196923
779370
399347
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine fgfr3 fgfr3.L fgfr3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas092f08      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards FGFR3 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Fgfr3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR fgfr3 ZFIN Ensembl
chicken
GEISHA FGFR3 Ensembl
fruit fly
worm
WORMBASE
Publications
First Fibroblast growth factor (FGF) 3 from Xenopus laevis (XFGF3) binds with high affinity to FGF receptor 2., J Biol Chem 1995  
Most Recent Bioinformatics Screening of Genes Specific for Well-Regenerating Vertebrates Reveals c-answer, a Regulator of Brain Development and Regeneration., Cell Rep 2019                                
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 5 terms 6 terms
PANTHER fgfr3
KEGG Pathways K05094 K05094 K05094
KOG [T] Fibroblast/platelet-derived growth factor receptor and related receptor tyrosine kinases
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks fgfr3
Morpholinos fgfr3 MO1 , fgfr3 MO2 fgfr3 MO1 , fgfr3 MO2 fgfr3 MO1 , fgfr3 MO2
ORFs fgfr3.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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