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Summary Expression Gene Literature (17) GO Terms (18) Nucleotides (364) Proteins (30) Interactants (135) Wiki
XB-GENEPAGE-479940
Gene Symbol:
tll1

Gene Name:
tolloid like 1

Synonyms:
xolloid-like metalloprotease , Tll , Xlr , Xolloid-related , Xolloid-like ( Add synonyms , Nomenclature history )

Gene Function:
metalloprotease

Protein Function :
Protease which processes procollagen C-propeptides, such as chordin. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and ske...[+]



Interactants:
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Diseases: 


Disease Ontology:
atrial heart septal defect 6

OMIM:
ATRIAL SEPTAL DEFECT 6; ASD6

External Links:
 
Xenbase Gene ID XB-GENE-479941 XB-GENE-17344589 XB-GENE-865326
Gene Symbol tll1 tll1.L tll1.S
Chromosome Chr01 Scaffold62 chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100495742
108704955
399178
mRNA NCBI Nucleotide NCBI Nucleotide RefSeq
Protein NCBI Protein NCBI Protein NCBI Protein NCBI Protein RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tll1 tll1.L tll1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TLL1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tll1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tll1 Ensembl
zebrafish
ZFIN, AGR tll1 ZFIN Ensembl
chicken
GEISHA TLL1 Ensembl
fruit fly
worm
Publications
First The astacin family of metalloendopeptidases., J Biol Chem 1991  
Most Recent Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer., Front Physiol 2019  
All View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 0 term 6 terms
PANTHER tll1
KEGG Pathways K09608
KOG [O] Meprin A metalloprotease
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tll1
Morpholinos tll1 MO1 tll1 MO1 tll1 MO1
ORFs tll1 ORF1
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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