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Summary Expression Gene Literature (116) GO Terms (9) Nucleotides (155) Proteins (33) Interactants (658) Wiki
Gene Symbol: casp3.2

Gene Name: caspase 3, gene 2

Synonyms: CASP-3 , Apopain , xCPP32 , caspase 3 , caspase-3 ( Add synonyms , Nomenclature history )

Gene Function: apoptotic cysteine protease

Protein Function :
Important mediator of apoptosis. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond.

Interactants: Loading ...
Diseases:  External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
Xenbase Gene ID XB-GENE-479960 XB-GENE-17335907 XB-GENE-865327
Gene Symbol casp3.2 casp3.2.L casp3.2.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100151728
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine casp3.2 casp3.2.L casp3.2.S
MOD Entrez Gene Genetic Phenotypes Gene Expression
OMIM:Gene, HGNC, GeneCards CASP3 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
MGI, AGR Casp3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
ZFIN, AGR ZFIN, AGR casp3a casp3b ZFIN Ensembl
fruit fly
First Induction of apoptosis and CPP32 expression by thyroid hormone in a myoblastic cell line derived from tadpole tail., J Biol Chem 1997  
Most Recent Mcl1 protein levels and Caspase-7 executioner protease control axial organizer cells survival., Dev Dyn 2020                
All View All Papers 20 paper(s) referencing morpholinos 4 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 3 terms 3 terms
PANTHER casp3.2
KEGG Pathways K02187 K02187 K02187
KOG [D] Caspase, apoptotic cysteine protease
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks casp3.2
Antibodies Casp3 Ab1 , Casp3 Ab2 , Casp3 Ab3 , Casp3 Ab4 , Casp3 Ab5 , Casp3 Ab6 Casp3 Ab3 , Casp3 Ab1 , Casp3 Ab4 Casp3 Ab1 , Casp3 Ab2 , Casp3 Ab3 , Casp3 Ab4 , Casp3 Ab5 , Casp3 Ab6
Morpholinos casp3 MO1 , casp3 MO2 casp3 MO1 , casp3 MO2 casp3 MO1 , casp3 MO2
ORFs casp3.S ORF1
Clones Horizon Source BioScience Horizon EXRC Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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