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Summary Expression Gene Literature (27) GO Terms (19) Nucleotides (189) Proteins (49) Interactants (625) Wiki
XB-GENEPAGE-481381
Gene Symbol:
foxc2

Gene Name:
forkhead box C2

Synonyms:
fd-4 , XFD-4 , MFH-1 , Mfh1 , fkh7 , foxc2-a , foxc2-b ( Add synonyms , Nomenclature history )

Gene Function:
forkhead domain transcription factor

Protein Function :
Transcriptional activator. May be involved in the dorso-ventral patterning of the mesoderm.


InterPro :
GDA1 CD39 NTPase , TF fork head CS 2 , WH DNA-bd sf , WH-like DNA-bd sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
yellow nail syndrome [+]

OMIM:
LYMPHATIC MALFORMATION 5; LMPHM5 [+]

External Links:
1/6
 
Xenbase Gene ID XB-GENE-481382 XB-GENE-865122 XB-GENE-6254394
Gene Symbol foxc2 foxc2.L foxc2.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 407875
735030
399191
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine foxc2 foxc2.L foxc2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FOXC2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Foxc2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Foxc2 Ensembl
zebrafish
chicken
GEISHA FOXC2 Ensembl
fruit fly
worm
Publications
First A fork head related multigene family is transcribed in Xenopus laevis embryos., Int J Dev Biol 1996    
Most Recent Lineage tracing of sclerotome cells in amphibian reveals that multipotent somitic cells originate from lateral somitic frontier., Dev Biol 2019          
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 10 terms 10 terms
PANTHER foxc2
KEGG Pathways K09396 K09396 K09396
KOG [K] Transcription factor of the Forkhead/HNF3 family
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks foxc2
Mutants Xtr.foxc2emHorb
Morpholinos (on-target & off-target) foxc2 MO1 foxc2 MO1 foxc2 MO1
ORFs foxc2 ORF1 foxc2.L ORF1
Clones EXRC Horizon Source BioScience EXRC Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info