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Summary Expression Gene Literature (27) GO Terms (18) Nucleotides (187) Proteins (45) Interactants (625) Wiki
XB-GENEPAGE-481381
Gene Symbol:
foxc2

Gene Name:
forkhead box C2

Synonyms:
fd-4 , XFD-4 , MFH-1 , Mfh1 , fkh7 , foxc2-a , foxc2-b ( Add synonyms , Nomenclature history )

Gene Function:
forkhead domain transcription factor

Protein Function :
Transcriptional activator. May be involved in the dorso-ventral patterning of the mesoderm.


InterPro :
GDA1 CD39 NTPase , TF fork head CS 2 , WH DNA-bd sf , WH-like DNA-bd sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
yellow nail syndrome [+]

OMIM:
LYMPHOCYTIC MALFORMATION 5; LMPHM5 [+]

External Links:
1/6
 
Xenbase Gene ID XB-GENE-481382 XB-GENE-865122 XB-GENE-6254394
Gene Symbol foxc2 foxc2.L foxc2.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 407875
735030
399191
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq Swiss-Prot RefSeq Swiss-Prot
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine foxc2 foxc2.L foxc2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FOXC2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Foxc2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Foxc2 Ensembl
zebrafish
chicken
GEISHA FOXC2 Ensembl
fruit fly
worm
Publications
First A fork head related multigene family is transcribed in Xenopus laevis embryos., Int J Dev Biol 1996    
Most Recent Lineage tracing of sclerotome cells in amphibian reveals that multipotent somitic cells originate from lateral somitic frontier., Dev Biol 2019          
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 10 terms 10 terms
PANTHER foxc2
KEGG Pathways K09396 K09396 K09396
KOG [K] Transcription factor of the Forkhead/HNF3 family
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks foxc2
Mutants Xtr.foxc2emHorb
Morpholinos foxc2 MO1 foxc2 MO1 foxc2 MO1
ORFs foxc2 ORF1 foxc2.L ORF1
Clones EXRC Horizon Source BioScience EXRC Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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