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Summary Expression Gene Literature (4) GO Terms (28) Nucleotides (166) Proteins (32) Interactants (352) Wiki
XB-GENEPAGE-481538
Gene Symbol:
f2

Gene Name:
coagulation factor II, thrombin

Synonyms:
coagulation factor II ( Add synonyms , Nomenclature history )

Gene Function:
blood coagulation

Protein Function :
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, ...[+]


InterPro :
NNMT TEMT trans , SAM-dependent MTases , TFIIF beta N , TFIIF beta [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
prothrombin deficiency [+]

OMIM:
STROKE, ISCHEMIC [+]

External Links:
 
Xenbase Gene ID XB-GENE-481539 XB-GENE-865465 XB-GENE-17331609
Gene Symbol f2 f2.L f2.S
Chromosome Chr4 chr4L chr4S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 548514
443652
446352
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine f2 f2.L f2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards F2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR F2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR F2 Ensembl
zebrafish
ZFIN, AGR f2 ZFIN Ensembl
chicken
GEISHA F2 Ensembl
fruit fly
worm
Publications
First An atlas of differential gene expression during early Xenopus embryogenesis., Mech Dev 2005                                                                                                                                                          
Most Recent Transcriptomic analysis identifies early cellular and molecular events by which estrogen disrupts testis differentiation and causes feminization in Xenopus laevis., Aquat Toxicol 2020  
All View All Papers 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 5 terms 5 terms
PANTHER f2
KEGG Pathways K01313 K01313 K01313
KOG [E] Trypsin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks f2
ORFs f2.L ORF1 f2.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info