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Summary Expression Gene Literature (181) GO Terms (29) Nucleotides (122) Proteins (42) Interactants (1597) Wiki
XB-GENEPAGE-481643
Gene Symbol:
dkk1

Gene Name:
dickkopf WNT signaling pathway inhibitor 1

Synonyms:
dickkopf-1 , Xdkk-1 , dkk-1 , dkk , xdkk1 , Dickkopf1 ( Add synonyms , Nomenclature history )

Gene Function:
secreted wnt antagonist

Protein Function :


InterPro :
Tetraspanin/Peripherin , Tetraspanin , Tetraspanin EC2 sf , ZCCHC3 [+]

Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-481644 XB-GENE-17337757 XB-GENE-865473
Gene Symbol dkk1 dkk1.L dkk1.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 549037
108696072
373592
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein TrEMBL NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine dkk1 dkk1.L dkk1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DKK1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Dkk1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Dkk1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR dkk1b dkk1a ZFIN Ensembl
chicken
GEISHA DKK4 Ensembl
fruit fly
worm
Publications
First Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction., Nature 1998  
Most Recent Combinatorial transcription factor activities on open chromatin induce embryonic heterogeneity in vertebrates., EMBO J 2021                          
All View All Papers 44 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 28 terms 3 terms 5 terms
PANTHER dkk1
KEGG Pathways K02165 K02165 K02165
KOG [T] Proteins containing Ca2+-binding EGF-like domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks dkk1
Antibodies Dkk1 Ab1 Dkk1 Ab1
Morpholinos (on-target & off-target) dkk1 MO1
Clones EXRC Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

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