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Summary Expression Gene Literature (10) GO Terms (32) Nucleotides (136) Proteins (40) Interactants (205) Wiki
XB-GENEPAGE-482527
Gene Symbol:
foxo1

Gene Name:
forkhead box O1

Synonyms:
foxo1a , xFoxO1 ( Add synonyms , Nomenclature history )

Gene Function:
forkhead domain transcription factor

Protein Function :
Transcription factor that regulates metabolic homeostasis in response to oxidative stress. Binds to the consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with co...[+]


InterPro :
GAR dom , CH dom sf , GAS2 , GAR dom sf [+]

Interactants:
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Diseases: 


Disease Ontology:
alveolar rhabdomyosarcoma

OMIM:
RHABDOMYOSARCOMA 2; RMS2

External Links:
 
Xenbase Gene ID XB-GENE-482528 XB-GENE-482532 XB-GENE-17332153
Gene Symbol foxo1 foxo1.L foxo1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 493378
444991
108709932
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine foxo1 foxo1.L foxo1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FOXO1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Foxo1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Foxo1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR foxo1a foxo1b ZFIN Ensembl
chicken
GEISHA FOXO1 Ensembl
fruit fly
worm
Publications
First The FoxO-subclass in Xenopus laevis development., Gene Expr Patterns 2004      
Most Recent The regulation of Akt and FoxO transcription factors during dehydration in the African clawed frog (Xenopus laevis)., Cell Stress Chaperones 2020  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 31 terms 26 terms 4 terms
PANTHER foxo1
KEGG Pathways K07201 K07201 K07201
KOG [K] Transcription factor of the Forkhead/HNF3 family
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks foxo1
Morpholinos (on-target & off-target) foxo1 MO1
ORFs foxo1 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info