fzd7 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (58)

Nucleotides (360)

Interactants (229)

XB-GENEPAGE-483730

Gene Symbol: fzd7 Gene Name: frizzled family receptor 7 Synonyms: Fz-7, Xfz7, frizzled-7, frizzled7, frizzled 7, frz7, frz-7, fz7 Add Xenopus synonyms Gene Function: transmembrane receptor in the wnt signaling pathway Interactants: dvl2(26) , wnt11b(15) , wnt11(11) , wnt8a(11) , myc(10) , t(10) , wnt5a(10) View All	1/5

XB-GENE-483731

XB-GENE-483735

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001016741\|Xenopus (Silurana) tropicalis frizzled family receptor 7 (fzd7), mRNA TGGGAAAGTACGTTGAAGTTTCAGAGGAATAAGCGAAAGTTCCTCGGATTGTGCATGTAAGAGCGTGAAAACGGACGCGCGTAAGGAATCGGTGCGCTGAGCTGCTCTCTGTATCCCGAGTTAGAGAAGGAGCGGACTCGTACAGAGAAGGAGCGGACTCGTACGGAGAAGGAGCGGACTCGTACGGAGAAGGAGCGGACTCGTACAGAGAAGGAGCGGAGAAGTTCCGAAAGAGGAGAATTAGCTGGTTTGGCCTCACTCTCCAGCCCCCCCTGCTGTCTGCAGAGCCCCGCGAATCATCACCTGTTGCCGCCCGGGTCCCGGCATGTTCGCTACGGTCTCCCTGCTGTTCTGCCTACTCCTGCAGCCCTCCCCATCTGCCCAGCAGTACCACGGAGAAAAGGGCATCTCCGTGCCCGACCATGGATTCTGCCAGCCCATTTCCATACCTCTATGCACGGACATCGCATACAATCAGACCATCATGCCCAATCTGCTCGGACACACCAACCAGGAGGACGCGGGGCTGGAGGTGCACCAGTTCTATCCGCTGGTGAAAGTGCAGTGTTCCCCGGAGCTGCGCTTCTTCTTGTGCTCCATGTACGCCCCGGTGTGCACCGTGCTGGAGCAGGCCATTCCCCCCTGCCGGTCCCTGTGCGAGAGAGCCAGGCAGGGCTGCGAGGCGCTCATGAACAAGTTCGGCTTCCAGTGGCCGGAGCGGCTGCGCTGTGAGAATTTCCCGATACACGGAGCGGGGGAGATCTGCGTGGGGCAGAACACTTCGGATAACAGCCCGTCCGGCCCCACCGCCCGGCCCACCCCTTACCTGCCGGACAGTATCACCTTCCACCCTCACCTCAACCGGGACTTCACCTGCCCGCGGCAGCTCAAGGTGCCCCCCTACCTGGGCTACCGCTTTCTGGGCGAGAAGGACTGCGGCGCCCCCTGCGAGCCGGGCAAGGCCAATGGGCTCATGTACTTTAAGGAGGAAGAAGTGCGCTTCGCCCGGCTGTGGGTGGGCATCTGGGCCATCCTGTGCGGCATCTCCACACTCTTCACCGTGCTCACCTACCTGGTGGATATGCGGCGTTTCAGCTACCCCGAGCGGCCCATCATCTTCCTGTCCGGCTGCTACTTCATGGTGGCCGTGGCTTACACCGCGGGGTTCCTGCTGGAGGAGCGGGGGGTGTGCGTGGAGCGCTTCTCGGAGGACAGTTACCGGACTGTGGCGCAGGGCACCAAGAAGGAGGGCTGCACCATCCTCTTCATGATCCTCTACTTCTTCGGCATGGCCAGCTCCATCTGGTGGGTTATACTGTCCCTTACCTGGTTCCTGGCTGCGGGCATGAAGTGGGGGCACGAAGCCATCGAGGCCAACTCGCAATACTTCCACTTGGCAGCCTGGGCAGTGCCCGCAGTGAAGACCATCACCATCCTGGCTATGGGGCAGGTGGATGGGGACATACTGAGCGGGGTGTGTTACGTGGGCATCAACAGCGTGGACTCCCTGAGGGGCTTCGTACTCGCCCCCCTCTTCGTGTACCTGTTCATCGGCACCTCCTTCCTGCTGGCCGGCTTCGTGTCCCTGTTCCGCATCAGGACCATTATGAAACACGATGGCACCAAAACGGAGAAGCTGGAGAAACTGATGGTGCGCATCGGGGTGTTCAGCGTCATGTACACTGTGCCGGCCACCATCGTGCTGGCTTGTTACTTCTACGAGCAGGCCTTCAGGGACACATGGGAAAAGACCTGGCTGGTACAGACCTGCAAAGGCTTTGCTGTGCCCTGTCCCAACTACAACTTTGCCCCCATGAGCCCGGACTTCACGGTCTTTATGATCAAATACTTAATGACCATGATTGTTGGCATCACCTCCAGCTTTTGGATTTGGTCTGGTAAAACCCTACAGTCCTGGCGCAGGTTTTATCACAGGCTCAGTAATGGCGGCAAGGGGGAAACTGCAGTATGAACATGGGGCAACACAGGGCCTCTACTGGAATTAAAGGGACTTTTGTTTTACTGGTACTAAAGTTCACTGGGGACATCCCATGAAAGCCCTCTTAATGCACATTATTTCTCCCCATCAAAGAATTCTTCATAATGAAGTGCTTGGGCTGACCCAGTCTGGACTATAGGGTTACTAGCTGGAAGTGGTTTGGGTCTAATGGGGTGGGTGTGGAAGCTGTGCAGATTTAGCATTGTTGAAACCAATTTTTTTTTATCCTGTAGCACTACAGCTGTTAAACTACAACTCCCAGTATCACCTAACGGCTGTTAAGGGTGCCAGGGGTTGTTACACAACAAATGGAGGGCTCAGGTTAGACATCTGATAGTTGGTGGTTGAGTGGGGGCCAGTTTAACACAGGGTATAGTAGGAAATCCAATATGGAAGCAGATATATGTTAATGTGTAACTTTGGCATCTGTTATTCATTCCCTCACTTGCATTATGTCACACAGCAGTAGTTAAAAGGCCACTAATCCTAAATGCCTATAAAATTCTGATCAAGCTCACAAATGTGTACATGTTAATGTCTTCACACAATGGCAGATAGCATGATATCTCAGAACAAAAGTGCATGGTTTCTTTGTCTCGGTGTGATGTATTCTGTTTTCCCTGCCTTTTTTAGGCTTTTCAGACAGGAAGTCTGATAAGGGCAACAAATGCTTCCCCCATTATCATATTTTGGTTTTAATGCATTTTCTCCCAGCTCAAGTTCCTATGCATGTATATGTACATTTGTGTTTGCTACAGCTCTTTCAAACATTGACTTGTGTTAGTGCTCTTGTTGGCCCTTACATTTTTTTGCTGCCAGTCTGGCTTGCGGTAACAGCCACACTGCCTGCTAAATAGATTGCTATTACCAGTGATGGGTATACCATATGGAATAGATATCAGCCAGTAACATTCCTGCATCTGTCATTTACTCAGCTGCTAGGCACAGAGATTTTTTATGTTTACCTAACAGATCAAGGCTTGTGCATGGTAAATACTTTGTGTCCCTTAAGCACCCAGCAGGCAGTTAATTAAAGTTCCTCTGAATAGGGCTTCACCTAACCAGCAGCTGGGCAAATAGTGCCTTTTGGTAGAGAGTGGCCCCCACTGTTATGTCAACAAGGCATCATACATAAAATATATTTTAATTCAGATTCTACCCAATGTTAGACAAACTTTCACCGTACTTTTTTTTTATTCAAGAGTATTTGCACTGCAGGGGGTATAATATTGCTCTCTCTCCTCCATTCCTCAATTGTTTTTTAAATTGGCATTATTGATCAGCTATCCTTTGTGGGATTAGGGTGTTTGCACTGGTTATCTGGGTCAGATCTACTATATTGAAGAATTTGAATGAATTTGTGCCTGTATAGCCAGTAGCTTGTAAGTGATATATCTCTTTCAAATCTGAACTGTATAGTTTCTTCTGTATAATGTCTAATTAACATTTCATATTAGACCAGTCCCTGCAAATGTATCCTATAATGCAAAGCCATGCAGTGTTGGAAACGCCTCTTGTAATGAAAGATAGCAGATCAGTTATATGTAAATTTCTTGTTTATTGCCCTACATTAAATGCATAATACGGAGTTAATCTGCTAAATAAACCCCTATGTCTTCCCCATGTTCATTCTGTTGTATTATATGGGGAGGCTGTTATGCATTGCCTTTTCTTTAGCGGATTAACTCTGAACATTCCCCATAGCAAAAAACACTTTCAGATCTGGGAATTAAGATTTGGCATACAAGGTTTTTTTTGTTTTGTTTTTTTTTTTTTAATCAGCCCTAATGTATTGTCTGCACAACCCATCTAGATTGTTTTACAGAAGGCTTTTTTTGTGATGGGGAAAGTGACCACAATAAACTTCCAGGGATCTTGGCAATTGCTGCATAATATGTATTTTTTAAAGTCAGATACTATGTATGGAATTAAGATTATTTTAATAATTTTTTTGTGCATGTCATCTTAAACAAATGAAGACTACATTGTTTATATTTTTTGTATATAACTGTACTATTTTGTACTAAGATATATATATATGTATTTATATGTTTCTACTTTTTGACTTAATGGCAAGACAAGCCTCACTTTATCTTGTGTACAGATCACTCAATAAAGCCTTCTTTTTTTAGGT	Refseq >NM_001085885\|Xenopus laevis frizzled family receptor 7 (fzd7), mRNA CCGGGGGTGGCTATCTAGTTTGCAGTTACGGAGATATAAGTGAAAGTTGCTCGCGTCCTGCGTTTATATGAGCGGGAATACGGCCGCGCGTATGAAGTCGGCGCGCTGAACTACTTTGTGTCTGAATCTGCCAGTTTGTACGAAGTTCGTCAAGGCGAGAATCCGCAGCTTTCTCCTCACTTTCCAGCTCCCCCTGCTGTCCAGAGATCACTTGTTGGAGCCGGCCGGGGAGTCAGCATGTCCTCTACAGTCTCGCTGCTGTTCTGCTGCCTATTCCTGCAGCTCTGCCCGTCTGCCCAGCAGTACCACGGGGAGAAGGGCATCTCGGTGCCTGACCATGGCTTCTGCCAGCCCATCTCCATCCCTCTGTGCACAGACATCGCCTACAACCAGACCATCATGCCCAATCTGCTCGGACACACCAACCAGGAGGACGCGGGGCTGGAGGTGCATCAGTTCTATCCGCTGGTGAAGGTTCAGTGTTCCCCGGAGCTGCGCTTCTTCCTGTGCTCCATGTACGCGCCGGTTTGCACCGTGTTGGAACAGGCCATCCCCCCGTGCCGGTCGCTGTGCGAGAGAGCCAGGCAGGGCTGCGAGGCGCTCATGAACAAGTTCGGCTTCCAGTGGCCCGAGCGGCTGCGCTGTGAGAATTTCCCGGTACACGGGGCGGGGGAGATCTGCGTGGGACAGAACACTTCAGATAACAGCCCGTCCGGCCCCACCGCTCGGCCCAGCCCTTACCTGCCGGACAGTATCACCTTCCAGCCGCACCCCCACCGGGACTTTACGTGCCCGCGTCAGCTCAAAGTGCCCCCCTACCTGGCCTACCGCTTCCTGGGAGAGAAGGACTGTGGCGCTCCCTGTGAGCCGGGCAAAGCCAACGGGCTGATGTACTTTAAGGAGGAGGAGGTGCGCTTCGCCCGGCTCTGGGTGGGTATCTGGGCGATCCTGTGCTGCATCTCCACGCTCTTCACTGTACTCACTTACCTGGTGGACATGCGACGCTTCAGTTACCCCGAGCGGCCCATCATCTTCCTGTCCGGCTGTTACTTCATGGTGGCCGTGGCTTACACTGCGGGCTTCCTGCTGGAGGAGCGGGCGGTGTGCGTGGAGCGCTTCTCGGAGGACAGTTACCGGACAGTGGCGCAGGGCACCAAGAAGGAGGGCTGTACCATTCTCTTCATGATCCTCTACTTCTTCGGCATGGCCAGTTCCATCTGGTGGGTGATCCTGTCCCTCACCTGGTTCCTGTCGGCGGGAATGAAGTGGGGACACGAGGCTATCGAGGCAAACTCTCAGTACTTCCACTTGGCGGCCTGGGCAGTGCCCGCGGTAAAGACCATCACTATTCTGGCCATGGGGCAAGTGGACGGGGACGTGCTGAGCGGGGTGTGTTACGTGGGCATCAACAGCGTGGACTCTCTGCGGGGCTTCGTGCTGGCCCCCCTGTTCGTGTACCTGTTCATCGGCACGTCCTTCCTGCTGGCCGGCTTCGTGTCGCTGTTCCGCATCAGGACCATCATGAAACACGACGGCACCAAGACGGAGAAGCTGGAGAAGCTGATGGTGCGCATCGGGGTGTTCAGTGTGATGTACACGGTGCCGGCCACCATCGTGCTGGCGTGTTACTTCTACGAGCAGGCCTTCAGGGACACCTGGGAAAAGACCTGGCTGGTTCAGACGTGTAAAGGCTACGCCGTGCCCTGTCCCAACTACAACTTTGCCCCCATGAGCCCGGACTTCACGGTGTTTATGATCAAGTACTTAATGACCATGATCGTGGGCATCACCTCCAGCTTTTGGATCTGGTCGGGCAAAACCCTACAGTCCTGGCGCAGGTTCTACCACAGACTGAGCAATGGCAGCAAAGGGGAGACTGCGGTGTGAACGTGGGGCAACACCTACTGGACTTAAAGGGACTTTTCATTTTACTGCTACTCAAGTTTGGCTGGGACATTCATGGAAAGCCCTCTCAATGCACATTATTTCTAGCCATCAAACTATTCTTCCAAATGAAGTGACTTGGGCTGACCCAGTCTGGACTATAGGGTTACGAGCTGCAAGTGGGTTGGATTTGATGGGGAGGGTGTTCTGGCAGACTTGGCATCATTTAAAGCAAATGTTTTTTTTTCCTTTGTATCCTGTAGCACTACAGCTGCTAAACTACAACTCCCAGGATGTTGCTCAACAAGTGCAGGGTTCACGTTGCTCATCTGATCGTTGTTGGTTAGTTAGTTAAGTGGGGCCGGTTTTACACAGATACAGTAGCAGGGAAGAGAGGACTAAAGAAGAAATGTGCTTAATATGTAACTTTGGCATCTGTTATTCATTGCCCCGCTTGCATTATGTCTCACAGCAGGAGATAAAGGAACACTAATCCCAAAAGCCGATAACATTCCGAGCAAGCTCACAAATGTGTGTATACATGTAAATGTCTTCATACAATGGCAGATAGCATGGTATCTCACAACGCAAGCACATGAACTCTTTGTCTCCCTGCAATGTATTATTCTGTTATCCCTTTATTTGCTTTTTAGACTTTTCATACAGGAAGTCTGATAAGGGCAACAAATACTTCCCTCCATGATCACATCTGCCTTCTAATGCATTTTCTTCCAGCTCAGGTTTCTGTGAGTGTATATGCACATTTGTGTTTGCTACAGCTCTCTCACTGACTTGTATTTAGCGCTCTCAGCCCTTTGTTTGGCTTGCAGTGACTATCACATTGCCTGAGAAATGGATTGATATTAGCAGTGATAGGGGTGCCACATGGAATAGATATCAGCCAGTAACATTCCTGCATCTGTCATTTGCTCAGCTGCTAGGCTTAGGGATGTTTCGTGTTTACCTAACAGATCAAGGCTTGTGGATGGTAAATACTTTGTGTCCCTTAAGCACCCAGCAGGCAGTTAATTAAAGTTCCTCTGAATAGGGCTTCACCTAACCAACAGCTGGGCAAATAATGCCTTTTGCTTGAGACTGGCCCCAACTGTTATGTCAACAAGGCATCATTCATACAATATATTTTAATTCCGTATCTCCCAAGTGTTAATGCAGACAAACTTTCCCCTATACATTTTATTTTTGGAGTATTTGCACTGCAGTGGGTATGACCTTGCTGGGAAACTGTGTTATGCCCAAGCCCCCCCCCCTTCCTTCCCCTTTTTTTCCATTCCAAATTTTTTTTTTAACATTAGCATTATTGATCAGCTATTCTTTGTGGAATTAAGGTGTTGACACTTGTTAACTGGGTCCAGCAGTGAAGAGGTTTTAGCCTTCCTTTATAAGAAATATTTCTCAGATACTGTATTTAATCAATTTGTGCCTGTATAGCCAGCGGCTTGTTGGTCCGTGCCTGCAAATGTATCCTATAATGCAGTGTTGGAAAATTCTTTTGGTATGAAAGATAGCAGATTTCATTCAGTTTTCAATTTCATGTTTATTCTCACATTAAATGCATAATACCGAGTTGATCTGCTAAATAAAACCTCATGCCTTCCCCCAATTGTGTTGTATAATATTAGGAGGTTGATATGCATAGCCATTTCTTTGGCAGATCAACTCCATCTGAACAATTGCTATAGTGAAGGGAATTTTGGCATACAAGTTGCTTTTTTTTTTTTTTTTAAATGAGCCCTAATATGTTGTCTGCACAACCCATCAAGTGCGTTTTTTCTGAAGGCTTTCTTTTTGTGATGGGGAAAGTGACCACAAAAAACTTCCAGGGATCTTGGCAATTGCTGCATAAAATGTATTTTTTAAAGTCAGATACTATGTATGAAATTAAAGATTATTTTAATAAAATTTTTGTGCATGTCATCATACAGCAAATGAAGACTACATTGTTTATATATTTTTTGTATATAACTGTACTATTTTGTACGAAGATATATATATGTATTTATGTTTCTACTTTTTGACAAATGAAAAGACAGCCTCACTTTATCTTGTGTACAGATCACTCAATAAAGCCTTCTTTTTAGGTAAAAAAAAAAAAA
Protein		Refseq >NP_001016741\|frizzled-7 precursor [Xenopus (Silurana) tropicalis] MFATVSLLFCLLLQPSPSAQQYHGEKGISVPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPIHGAGEICVGQNTSDNSPSGPTARPTPYLPDSITFHPHLNRDFTCPRQLKVPPYLGYRFLGEKDCGAPCEPGKANGLMYFKEEEVRFARLWVGIWAILCGISTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAYTAGFLLEERGVCVERFSEDSYRTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDILSGVCYVGINSVDSLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVMYTVPATIVLACYFYEQAFRDTWEKTWLVQTCKGFAVPCPNYNFAPMSPDFTVFMIKYLMTMIVGITSSFWIWSGKTLQSWRRFYHRLSNGGKGETAV UniProtKB	Refseq >NP_001079354\|frizzled family receptor 7 precursor [Xenopus laevis] MSSTVSLLFCCLFLQLCPSAQQYHGEKGISVPDHGFCQPISIPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSLCERARQGCEALMNKFGFQWPERLRCENFPVHGAGEICVGQNTSDNSPSGPTARPSPYLPDSITFQPHPHRDFTCPRQLKVPPYLAYRFLGEKDCGAPCEPGKANGLMYFKEEEVRFARLWVGIWAILCCISTLFTVLTYLVDMRRFSYPERPIIFLSGCYFMVAVAYTAGFLLEERAVCVERFSEDSYRTVAQGTKKEGCTILFMILYFFGMASSIWWVILSLTWFLSAGMKWGHEAIEANSQYFHLAAWAVPAVKTITILAMGQVDGDVLSGVCYVGINSVDSLRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVFSVMYTVPATIVLACYFYEQAFRDTWEKTWLVQTCKGYAVPCPNYNFAPMSPDFTVFMIKYLMTMIVGITSSFWIWSGKTLQSWRRFYHRLSNGSKGETAV UniProtKB UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.48717 [+] Str.46224 Str.65136	Xl.633 [+] Xl.83692
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		66 expression image(s) for tropicalis and laevis

Phenotype		tropicalis	laevis
Smith Morpholino Screen		tneu065e03

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	FZD7
mouse		MGI	Fzd7	All(2) Targeted, other(1) Targeted, knock Out(1)
zebrafish		ZFIN ZFIN	fzd7a fzd7b	2 Lines(s) 4 Lines(s)

Publications
First:		Two novel Xenopus frizzled genes expressed in developing heart and brain. [Mech Dev 1999]
Most recent:		Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells. [Dev Biol 2013]
		View All Papers 14 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		G-protein coupled receptor activity non-G-protein coupled 7TM receptor activity oxidoreductase activity More[+] transmembrane receptor activity
Biological:		cell surface receptor linked signal transduction metabolic process multicellular organismal development
Cellular Component:		membrane
EC:
KOG:		[T] Smoothened and related G-protein-coupled receptors

Reagents		tropicalis	laevis
Clones			EXRC - 5 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.6502.1.S1_s_at	Xl.633.1.S2_at [+] Xl.633.1.S1_a_at Xl.633.1.S1_at Xl.633.2.S2_at Xl.633.2.S1_at
Affymetrix 2.0			Xl2.633.1.S2_at [+] Xl2.633.2.S2_at Xl2.633.1.S1_at Xl2.633.1.S1_a_at Xl2.633.2.S1_at

Symbol legend[+]