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Summary Expression Gene Literature (13) Nucleotides (58) Proteins (11) Interactants (115) Wiki
XB-GENEPAGE-484031

Gene Symbol: igf1r

Gene Name: insulin-like growth factor 1 receptor

Synonyms: xIGF-1R, xIGFR, xigf1r, igf-1r, XTK2 Add Xenopus synonyms

Gene Function: growth factor receptor, contains protein kinase domain

Interactants: igf1(7) , ins(7) , pax6(5) , insr(4) , otx2(4) , chrd(3) , igf2(3) View All

Disease Associations: INSULIN-LIKE GROWTH FACTOR I, RESISTANCE TO
 
Xenbase Gene ID XB-GENE-484032 XB-GENE-865040
Current JGI Annotation igf1r igf1r.S
Molecules tropicalis laevis
Gene GBrowse 8.0 GBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein Refseq UniProtKB
Genomic tropicalis laevis
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v7.2 gene model
Links
tropicalis 4.1 synteny Metazome
Expression tropicalis laevis
UniGene [+] Xl.269
Unigene EST Profile EST Profile
GEO data GEO
Images 0 expression image(s) for tropicalis and laevis
Phenotype tropicalis laevis
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Morphants
human
OMIM:Gene, HGNC IGF1R OMIM:270450
mouse
MGI Igf1r All available mutants
zebrafish
chicken
GEISHA IGF1R
Publications
First: Genes encoding receptors for insulin and insulin-like growth factor I are expressed in Xenopus oocytes and embryos. [Proc Natl Acad Sci U S A 1991]
Most recent: Using myc genes to search for stem cells in the ciliary margin of the Xenopus retina. [Dev Neurobiol 2012]
View All Papers 4 paper(s) referencing morpholinos
Functional Ontologies
GO: Molecular: ATP binding
epidermal growth factor receptor activity
protein kinase activity
More[+]
      Biological: protein amino acid phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
      Cellular Component: membrane
EC: now EC:2.7.10.1 and EC:2.7.10.2
KOG: [T] Insulin/growth factor receptor (contains protein kinase domain)
Reagents tropicalis laevis
CRISPR / TALEN CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon
geneservice/RZPD imagenes
Morpholino igf1r MO1 igf1r MO1
Affymetrix 1.0 Str.32073.1.S1_s_at [+] Xl.269.1.S2_x_at [+]
Affymetrix 2.0 Xl2.269.1.S1_at

Symbol legend[+]

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