Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (15) GO Terms (140) Nucleotides (96) Proteins (44) Interactants (233) Wiki
XB-GENEPAGE-484031
???displayGene.symbol???:
 igf1r

???displayGene.name???: 
insulin like growth factor 1 receptor

???displayGene.synonyms???
igf-1r , xIGF-1R , xigf1r , xIGFR , XTK2 [-] ( Nomenclature history )

???displayGene.geneFunction???
growth factor receptor, contains protein kinase domain

Protein Function :
This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1...[+]


InterPro :
Furin repeat, Rcpt L-dom sf, Kinase-like dom sf, Tyr kinase rcpt 2 CS, [+]

???displayGene.geneInteractants???
Loading ...

Diseases: 


MIM:
INSULIN-LIKE GROWTH FACTOR I, RESISTANCE TO; IGF1RES

External Links:
 
???displayGene.expression???                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info