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XB-GENEPAGE-484375
Gene Symbol:
irx5
Gene Name: iroquois homeobox 5
Synonyms:
iroquois-5
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Xiro5
( Gene Function: homeodomain transcription factor Protein Function
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Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Patterns the neuroec...[+]
Interactants:
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Diseases: OMIM:
HAMAMY SYNDROME; HMMS
External Links:
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Xenbase Gene ID | XB-GENE-484376 | XB-GENE-865076 | XB-GENE-17336278 | |||||
Gene Symbol | irx5 | irx5.L | irx5.S | Chromosome | Chr4 | Scaffold116 | chr4S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
100038201
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373841
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108715340
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mRNA |
NCBI Nucleotide
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser)
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | irx5 | irx5.L | irx5.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Expression of two novel mouse Iroquois homeobox genes during neurogenesis., Mech Dev 2000 |
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Most Recent |
Id genes are essential for early heart formation., Genes Dev 2017 ![]() |
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All | View All Papers 3 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 36 terms | 12 terms | 7 terms | |||||
PANTHER | irx5 | |||||||
KEGG Pathways | ||||||||
KOG |
[K] Transcription factor MEIS1 and related HOX domain proteins
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | irx5 | |||||||
Morpholinos (on-target & off-target) | irx5 MO1 | irx5 MO1 | irx5 MO1 | |||||
Clones | Horizon Source BioScience | Horizon Source BioScience | Horizon | |||||
Plasmids | Addgene | Addgene |
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