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Summary Expression Gene Literature (2) GO Terms (10) Nucleotides (240) Proteins (50) Interactants (111) Wiki
XB-GENEPAGE-485386
Gene Symbol:
arhgef12

Gene Name:
Rho guanine nucleotide exchange factor 12

Synonyms:
Larg ( Add synonyms , Nomenclature history )

Gene Function:
PDZ-domain containing guanine exchange factor

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
acute myeloid leukemia

OMIM:
LEUKEMIA, ACUTE MYELOID; AML

External Links:
 
Xenbase Gene ID XB-GENE-485387 XB-GENE-17345521 XB-GENE-865525
Gene Symbol arhgef12 arhgef12.L arhgef12.S
Chromosome Chr07 chr7L chr7S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 779951
108696425
398710
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq NCBI Protein RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine arhgef12 arhgef12.L arhgef12.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ARHGEF12 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Arhgef12 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Arhgef12 Ensembl
zebrafish
ZFIN, AGR arhgef12b arhgef12a ZFIN Ensembl
chicken
GEISHA ARHGEF12 Ensembl
fruit fly
worm
Publications
First Involvement of p114-RhoGEF and Lfc in Wnt-3a- and dishevelled-induced RhoA activation and neurite retraction in N1E-115 mouse neuroblastoma cells., Mol Biol Cell 2010                    
Most Recent Evolution of vertebrate central nervous system is accompanied by novel expression changes of duplicate genes., J Genet Genomics 2011                                                                                                                                                            
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 4 terms 4 terms
PANTHER arhgef12
KEGG Pathways K07532 K07532 K07532
KOG [T] Predicted guanine nucleotide exchange factor
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks arhgef12
Clones Horizon Source BioScience Horizon Horizon Source BioScience

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