Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (9) GO Terms (6) Nucleotides (1182) Proteins (40) Interactants (116) Wiki
XB-GENEPAGE-486874
Gene Symbol:
srsf1

Gene Name:
serine/arginine-rich splicing factor 1

Synonyms:
asf , sf2 , sfrs1 , sf2p33 , srp30a ( Add synonyms , Nomenclature history )

Gene Function:
alternative splicing factor

Protein Function :
May play a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing.


InterPro :
Aminotransferase-like , Aminotrans IV CS , Aminotrans IV , BCAT family [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-486875 XB-GENE-486879 XB-GENE-17339498
Gene Symbol srsf1 srsf1.L srsf1.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448766
399226
108708917
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine srsf1 srsf1.L srsf1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SRSF1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Srsf1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Srsf1 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR srsf1b srsf1a ZFIN Ensembl
chicken
GEISHA SRSF1 Ensembl
fruit fly
worm
Publications
First Overexpression of synaptophysin enhances neurotransmitter secretion at Xenopus neuromuscular synapses., J Neurosci 1995              
Most Recent The splicing factor SRSF1 modulates pattern formation by inhibiting transcription of tissue specific genes during embryogenesis., Biochem Biophys Res Commun 2016                  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 6 terms 0 term 0 term
PANTHER srsf1
KEGG Pathways K12890
KOG [A] Alternative splicing factor ASF/SF2 (RRM superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks srsf1
Morpholinos (on-target & off-target) srsf1 MO1
ORFs srsf1 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info