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Summary Expression Gene Literature (118) GO Terms (29) Nucleotides (135) Proteins (40) Interactants (1250) Wiki
XB-GENEPAGE-487457
Gene Symbol: gata4

Gene Name: GATA binding protein 4

Synonyms: xGATA-4 , gata-4 , xgata4 , gata4-a , gata4-b ( Add synonyms , Nomenclature history )

Gene Function: zinc finger transcription factor

Protein Function :
Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3'. Associated with cardiac specification and can regulate cardiac-specific transcription during embryogenesis. Activates the ex...[+]

Interactants: Loading ...
Diseases:  Disease Ontology: atrial heart septal defect 2 [+]

OMIM: TETRALOGY OF FALLOT; TOF [+]

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
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Xenbase Gene ID XB-GENE-487458 XB-GENE-487462 XB-GENE-6256576
Gene Symbol gata4 gata4.L gata4.S
Chromosome scaffold_13 chr5L chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549703
443781
399302
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL TrEMBL RefSeq TrEMBL RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine gata4 gata4.L gata4.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards GATA4 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Gata4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR gata4 ZFIN Ensembl
chicken
GEISHA GATA4 Ensembl
fruit fly
worm
WORMBASE
Publications
First GATA-4 is a novel transcription factor expressed in endocardium of the developing heart., Development 1993                  
Most Recent Recovery of the Xenopus laevis heart from ROS-induced stress utilizes conserved pathways of cardiac regeneration., Dev Growth Differ 2019                
All View All Papers 25 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 27 terms 5 terms 9 terms
PANTHER gata4
KEGG Pathways K09183 K09183 K09183
KOG [K] GATA-4/5/6 transcription factors
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks gata4
Morpholinos gata4 MO1 , gata4 MO2 , gata4 MO3 , gata4 MO4 gata4 MO1 , gata4 MO2 , gata4 MO3 , gata4 MO4 gata4 MO1 , gata4 MO2 , gata4 MO3 , gata4 MO4
ORFs gata4.L ORF1 gata4.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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